ସେଫାକ୍ଲୋର

ସେଫାକ୍ଲୋର
Clinical data
Trade names	Distaclor, Medacef, Keflor, others
Synonyms	Cephaclor
AHFS/Drugs.com	monograph
MedlinePlus	a682729
Pregnancy; category	AU: B1 ; US: B (No risk in non-human studies) ; ;
Routes of; administration	By mouth
Legal status
Legal status	℞ (Prescription only);
Pharmacokinetic data
Bioavailability	Well absorbed, independent of food intake
Metabolism	15% to 40%
Elimination half-life	0.6 to 0.9 hours
Excretion	Kidney
Identifiers
	IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}- 3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene- 2-carboxylic acid;
ECHA InfoCard	100.053.536
Chemical and physical data
Formula	C15H14ClN3O4S
Molar mass	୩୬୭.୮0 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(/Cl)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccccc3)N)C(=O)O.O;
	InChI InChI=1S/C15H14ClN3O4S.H2O/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7;/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23);1H2/t9-,10-,14-;/m1./s1 ; Key:WKJGTOYAEQDNIA-IOOZKYRYSA-N ;
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ସେଫାକ୍ଲୋର, ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ଏକ ବେପାର ନାମ ସେକ୍ଲୋର, ହେଉଛି ଏକ ଆଣ୍ଟିବାୟୋଟିକ୍ ଯାହା ନିମୋନିଆ, ମଧ୍ୟକର୍ଣ୍ଣ ସଂକ୍ରମଣ, ଷ୍ଟ୍ରେପ୍ ଗଳା, ସେଲୁଲାଇଟିସ୍ ଏବଂ ମୂତ୍ରନଳୀ ସଂକ୍ରମଣ ଭଳି ଜୀବାଣୁ ସଂକ୍ରମଣର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୩] ଏହାକୁ ଖାଦ୍ୟ ସହିତ ପାଟିରେ ନିଆଯାଏ । ^[୧] ଏହା ଏକ ମାସର ଛୋଟ ପିଲାମାନଙ୍କଠାରେ ମଧ୍ୟବ୍ୟବହୃତ ହୋଇପାରେ । ^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ରାସ, ତରଳ ଝାଡ଼ା, ଯୋନୀପଥ ପ୍ରଦାହ, ଅଇ, ଏବଂ ମୁଣ୍ଡବିନ୍ଧା ହୋଇପାରେ । ^[୩] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଉଦ୍‌ବେଗ, କମ୍ ଲୋହିତ ରକ୍ତ କଣିକା, ଗଣ୍ଠି ଯନ୍ତ୍ରଣା, ଆଲର୍ଜି ପ୍ରତିକ୍ରିୟା, ଜଣ୍ଡିସ୍ ଏବଂ ଗ୍ରନ୍ଥି ଫୁଲା ହୋଇପାରେ । ^[୧] ଗର୍ଭାବସ୍ଥାରେ କ୍ଷତି ଘଟାଇବା ଜଣା ନାହିଁ ଏବଂ ସ୍ତନ୍ୟପାନ କରାଇବା ସମୟରେ ଏହା ବ୍ୟବହାର କରାଯାଇପାରେ । ^[୧] ଏହା ଏକ ଦ୍ୱିତୀୟ ପିଢ଼ୀର ସେଫାଲୋସ୍ପୋରିନ୍ । ^[୪]

୧୯୭୫ ମସିହାରେ ସେଫାକ୍ଲୋର ପେଟେଣ୍ଟ ହୋଇଥିଲା ଏବଂ ୧୯୭୯ରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା। ^[୫] ^[୬] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ଏକ ଶୃଙ୍ଖଳାର ମୂଲ୍ୟ ସାଧାରଣତଃ ୧୦ ପାଊଣ୍ଡରୁ କମ୍ ଖର୍ଚ୍ଚ ହୁଏ । ^[୧] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ରାଶିର ମୂଲ୍ୟ ପ୍ରାୟ ୨୨ ଡଲାର୍ । ^[୭]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ "5. Infection". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 559–560. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)
↑ "A - Z Drug List from Drugs.com: Cefaclor". Drugs.com (in ଇଂରାଜୀ). American Society of Health-System Pharmacists. Archived from the original on 17 November 2021. Retrieved 27 November 2021.
↑ ^୩.୦ ^୩.୧ "Cefaclor Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 26 February 2021. Retrieved 30 December 2021.
↑ Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (in ଇଂରାଜୀ) (15th ed.). New York: McGraw-Hill. pp. 832–834. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-11-27.
↑ Nard, Craig Allen (2020). "7. Enforcing patent rights". The Law of Patents (in ଇଂରାଜୀ). New York: Wolters Kluwer. p. 694. ISBN 978-1-5438-1368-5. Archived from the original on 2021-12-11. Retrieved 2021-12-01.
↑ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 493. ISBN 9783527607495. Archived from the original on 2017-09-10. Retrieved 2020-12-31.
↑ "Cefaclor Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 30 December 2021.

[BNF82-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ "5. Infection". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 559–560. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)

[AHFS-2] "A - Z Drug List from Drugs.com: Cefaclor". Drugs.com (in ଇଂରାଜୀ). American Society of Health-System Pharmacists. Archived from the original on 17 November 2021. Retrieved 27 November 2021.

[AHFS2021-3] ୩.୦ ^୩.୧ "Cefaclor Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 26 February 2021. Retrieved 30 December 2021.

[Katzung2021-4] Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (in ଇଂରାଜୀ) (15th ed.). New York: McGraw-Hill. pp. 832–834. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-11-27.

[Nard2020-5] Nard, Craig Allen (2020). "7. Enforcing patent rights". The Law of Patents (in ଇଂରାଜୀ). New York: Wolters Kluwer. p. 694. ISBN 978-1-5438-1368-5. Archived from the original on 2021-12-11. Retrieved 2021-12-01.

[Fis2006-6] Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 493. ISBN 9783527607495. Archived from the original on 2017-09-10. Retrieved 2020-12-31.

[7] "Cefaclor Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 30 December 2021.

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