ବାଜେଡୋକ୍ସିଫେନ/କଞ୍ଜୁଗେଟେଡ ଇଷ୍ଟ୍ରୋଜେନ

ବାଜେଡୋକ୍ସିଫେନ/କଞ୍ଜୁଗେଟେଡ ଇଷ୍ଟ୍ରୋଜେନ
Combination of
Bazedoxifene	Selective estrogen receptor modulator
Conjugated estrogens	Estrogen
Clinical data
Trade names	Duavee, Duavive
AHFS/Drugs.com	monograph
MedlinePlus	a614004
data	US DailyMed: Duavee;
Pregnancy; category	AU: D ; US: X (Contraindicated) ;
Routes of; administration	By mouth
Legal status
Legal status	US: ℞-only ; EU: Rx-only ; ℞ (Prescription only);

ବାଜେଡୋକ୍ସିଫେନ/କଞ୍ଜୁଗେଟେଡ ଇଷ୍ଟ୍ରୋଜେନ, ବେପାର ନାମ ଡୁଭେ ଏବଂ ଡୁଭିଭ୍, ଋତୁବନ୍ଦ ସମୟରେ ହେଉଥିବା ଲକ୍ଷଣମାନଏବଂ ପରବର୍ତ୍ତୀ ସମୟରେ ହେଉଥିବା ଓଷ୍ଟିଓପୋରୋସିସ ରୋଗର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ଏକ ସ୍ଥିର ମାତ୍ରାର ଔଷଧ ମିଶ୍ରଣ । ^[୨] ଏହା ପାଟିରେ ଦିଆଯାଏ | ^[୩] ଏହାକୁ ସ୍ୱଳ୍ପ ମିଆଦି ବ୍ୟବହାର କରାଯିବା ଉଚିତ୍ ^[୩]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମାଂସପେଶୀ ସ୍ପାଜ୍ମ, ଅଇ, ତରଳ ଝାଡ଼ା, ବୁକୁଜ୍ୱାଳା, ମୁଣ୍ଡ ବୁଲାଇବା ଏବଂ ଯନ୍ତ୍ରଣା ହୋଇପାରେ । ^[୨] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ରକ୍ତ ଜମାଟ ବାନ୍ଧିବା, ଷ୍ଟ୍ରୋକ ଏବଂ ଏଣ୍ଡୋମେଟ୍ରିଆଲ୍ କର୍କଟ ହୋଇପାରେ। ^[୨] ଗର୍ଭାବସ୍ଥାରେ ଏହାକୁ ବ୍ୟବହାର କରିବା ଉଚିତ୍ ନୁହେଁ । ^[୩] ଏଥିରେ ବାଜେଡୋକ୍ସିଫେନ୍ ନାମକ ଏକ ସିଲେକ୍ଟିଭ୍ ଇଷ୍ଟ୍ରୋଜେନ୍ ରିସେପ୍ଟର ମଡ୍ୟୁଲେଟର ଏବଂ କଞ୍ଜୁଗେଟେଡ୍ ଇଷ୍ଟ୍ରୋଜେନ୍ ଥାଏ , ^[୪]

ଏହି ମିଶ୍ରଣକୁ ୨୦୧୩ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏବଂ ୨୦୧୪ରେ ୟୁରୋପରେ ଚିକିତ୍ସା ପାଇଁ ଅନୁମୋଦନ କରାଯାଇଥିଲା। ^[୨] ^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏକ ମାସର ଔଷଧର ମୂଲ୍ୟ ୨୦୨୨ ସୁଦ୍ଧା ପ୍ରାୟ ୧୮୦ ଡଲାର ଅଟେ ^[୬]

ଆଧାର

1 2 "Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy". Drugs.com. 16 February 2019. Archived from the original on 26 June 2020. Retrieved 23 June 2020.
1 2 3 4 "Selective Estrogen Receptor Modulators". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 11 January 2022. Retrieved 8 January 2022.
1 2 3 "DailyMed - DUAVEE- conjugated estrogens/bazedoxifene tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 10 May 2021. Retrieved 8 January 2022.
↑ "Bazedoxifene Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 19 April 2021. Retrieved 8 January 2022.
↑ "Duavive EPAR". European Medicines Agency (EMA). Archived from the original on 2020-06-10. Retrieved 2020-06-10.
↑ "Conjugated Estrogens and Bazedoxifene Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 16 April 2016. Retrieved 8 January 2022.

[Drugs.com_pregnancy-1] 1 2 "Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy". Drugs.com. 16 February 2019. Archived from the original on 26 June 2020. Retrieved 23 June 2020.

[Liv2022-2] 1 2 3 4 "Selective Estrogen Receptor Modulators". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 11 January 2022. Retrieved 8 January 2022.

[PI2022-3] 1 2 3 "DailyMed - DUAVEE- conjugated estrogens/bazedoxifene tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 10 May 2021. Retrieved 8 January 2022.

[AHFS2022-4] "Bazedoxifene Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 19 April 2021. Retrieved 8 January 2022.

[EPAR2022-5] "Duavive EPAR". European Medicines Agency (EMA). Archived from the original on 2020-06-10. Retrieved 2020-06-10.

[6] "Conjugated Estrogens and Bazedoxifene Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 16 April 2016. Retrieved 8 January 2022.

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