ଟେଡିଜୋଲିଡ

ଟେଡିଜୋଲିଡ
Clinical data
Trade names	Sivextro
Synonyms	TR-700, torezolid
AHFS/Drugs.com	monograph
MedlinePlus	a614038
Pregnancy; category	US: N (Not classified yet) ;
Routes of; administration	By mouth, intravenous
Legal status
Legal status	US: ℞-only ; EU: Rx-only ;
Pharmacokinetic data
Bioavailability	91%
Protein binding	70–90%
Elimination half-life	12 hours
Excretion	Feces
Identifiers
	IUPAC name (5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one;
ECHA InfoCard	100.249.430
Chemical and physical data
Formula	C17H15FN6O3
Molar mass	୩୭୦.୩୪ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C4O[C@H](CN4c3cc(F)c(c1ccc(nc1)c2nn(nn2)C)cc3)CO;
	InChI InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1 ; Key:XFALPSLJIHVRKE-GFCCVEGCSA-N ;
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ଇଂରାଜୀ ଲିଙ୍କ

https://or.wikipedia.org/wiki/Tedizolid

ଟେଡିଜୋଲିଡ (ଇଂରାଜୀ ଭାଷାରେ Tedizolid), ସିଭେକ୍ସଟ୍ରୋ ଏହାର ବିକ୍ରୟ ନାମ, ହେଉଛି ଏକ ଆଣ୍ଟିବାୟୋଟିକ ଯାହା ଚର୍ମ ଓ ତାହାର ସେଲୁଲିଟିସ୍ ଏବଂ ଚର୍ମ ଆବସେସ୍ ସହିତ ଚର୍ମ ଏବଂ ଚର୍ମ ଉପାଦାନର ସଂକ୍ରମଣ ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୩] ^[୨] ମେଥିସିଲିନ୍-ପ୍ରତିରୋଧୀ ଷ୍ଟାଫିଲୋକୋକସ୍ ଅରିଅସ୍ (MRSA) ଏଥିରେ ଅନ୍ତର୍ଭୁକ୍ତ | ^[୨] ଏହା ପାଟିରେ କିମ୍ବା ଧୀରେ ଧୀରେ ଏକ ଶିରାରେ ଇଞ୍ଜେକ୍ସନ ଦେଇ ଦିଆଯାଇପାରେ | ^[୩]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ବାନ୍ତି, ମୁଣ୍ଡବିନ୍ଧା, ତରଳ ଝାଡ଼ା ଏବଂ ବାନ୍ତି ହୋଇପାରେ ।^[୨] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ କ୍ଲୋସ୍ଟ୍ରିଡିଅମ ଡିଫିସିଲ ସଂକ୍ରମଣ ହୋଇପାରେ ।^[୩] ଗର୍ଭାବସ୍ଥାରେ ଏବଂ ସ୍ତନ୍ୟପାନରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ ।^[୩] ଏହ ଅକ୍ସାଜୋଲିଡିନୋନ୍ ଶ୍ରେଣୀର ଔଷଧ ଏବଂ ଜୀବାଣୁକୁ ପ୍ରୋଟିନ୍ ତିଆରି କରିବାରେ ରୋକିଥାଏ ।^[୨]

୨୦୧୪ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏବଂ ୨୦୧୫ରେ କାନାଡ଼ା ଏବଂ ୟୁରୋପରେ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ପାଇଁ ଟେଡିଜୋଲିଡ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୨] ^[୩] ^[୪] ଲିନେଜୋଲିଡର ବିକଳ୍ପ ଭାବେ ବିଶ୍ୱ ସ୍ୱାସ୍ଥ୍ୟ ସଂଗଠନର ଆବଶ୍ୟକୀୟ ଔଷଧ ତାଲିକାରେ ଏହାର ନାମ ଲିପିବଦ୍ଧ ଅଛି ।^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୬ ଦିନିଆ ଚିକିତ୍ସା କୋର୍ସର ଖର୍ଚ୍ଚ ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ ୨୩୦୦ ଡଲାର ଥିଲା । ^[୬] ଯୁକ୍ତରାଜ୍ୟରେ ଏହି ରାଶିର ମୂଲ୍ୟ ୮୬୨ ପାଉଣ୍ଡ ଅଟେ ।^[୭]

ଆଧାର

↑ "Sivextro- tedizolid phosphate tablet, film coated Sivextro- tedizolid phosphate injection, powder, lyophilized, for solution". DailyMed. 22 June 2020. Archived from the original on 26 October 2020. Retrieved 24 October 2020.
1 2 3 4 5 6 "Sivextro EPAR". European Medicines Agency (EMA). Archived from the original on 8 July 2020. Retrieved 5 July 2020. Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
1 2 3 4 5 "Tedizolid Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 25 January 2021. Retrieved 24 September 2021.
↑ Canada, Health (4 May 2016). "Health Canada New Drug Authorizations: 2015 Highlights". www.canada.ca. Archived from the original on 20 February 2020. Retrieved 24 September 2021.
↑ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
↑ "Tedizolid Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 7 June 2016. Retrieved 24 September 2021.
↑ BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 607. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)

[Sivextro_FDA_label-1] "Sivextro- tedizolid phosphate tablet, film coated Sivextro- tedizolid phosphate injection, powder, lyophilized, for solution". DailyMed. 22 June 2020. Archived from the original on 26 October 2020. Retrieved 24 October 2020.

[EPAR2021-2] 1 2 3 4 5 6 "Sivextro EPAR". European Medicines Agency (EMA). Archived from the original on 8 July 2020. Retrieved 5 July 2020. Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged.

[AHFS2021-3] 1 2 3 4 5 "Tedizolid Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 25 January 2021. Retrieved 24 September 2021.

[4] Canada, Health (4 May 2016). "Health Canada New Drug Authorizations: 2015 Highlights". www.canada.ca. Archived from the original on 20 February 2020. Retrieved 24 September 2021.

[WHO23rd-5] World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

[6] "Tedizolid Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 7 June 2016. Retrieved 24 September 2021.

[BNF80-7] BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 607. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)

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