ସେଫାଡ୍ରକ୍ସିଲ

ସେଫାଡ୍ରକ୍ସିଲ
Clinical data
Trade names	Duricef
Synonyms	Cephadroxil
AHFS/Drugs.com	monograph
MedlinePlus	a682730
Routes of; administration	By mouth
Legal status
Legal status	℞ (Prescription only);
Pharmacokinetic data
Protein binding	plasma protein
Metabolism	unknown
Elimination half-life	1.5 hours
Identifiers
	IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
ECHA InfoCard	100.051.397
Chemical and physical data
Formula	C16H17N3O5S
Molar mass	୩୬୩.୩୯ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C)C(=O)O.O;
	InChI InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1 ; Key:NBFNMSULHIODTC-CYJZLJNKSA-N ;
(verify)

ସେଫାଡ୍ରକ୍ସିଲ, ଏକ ବେପାର ନାମ ଡୁରିସେଫ, ହେଉଛି ଏକ ଆଣ୍ଟିବାୟୋଟିକ୍ ଯାହା ସାଧାରଣତଃ ଚର୍ମ ଓ କୋମଳ ତନ୍ତୁ ଏବଂ ମୂତ୍ରନଳୀରେ ଜୀବାଣୁ ସଂକ୍ରମଣର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୧] ^[୨] ଏହା ଉଭୟ ଗ୍ରାମ୍ ପଜିଟିଭ୍ ଏବଂ ଗ୍ରାମ-ନେଗେଟିଭ ସଂକ୍ରମଣ ପାଇଁ ବ୍ୟବହୃତ ହୋଇପାରେ । ^[୧] ଏହାକୁ କ୍ୟାପସୁଲ ଭାବରେ ପାଟିରେ ଦିଆଯାଏ । ^[୧] ବୃକ୍‌କ ସମସ୍ୟା ଥିଲେ ଏହାର ମାତ୍ରା ସଜାଡିବା ଆବଶ୍ୟକ ହୋଇପାରେ । ^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ବଦ‌ହଜମୀ ଏବଂ ଜିଭ ଘାଆ ହୋଇପାରେ । ^[୧] କବକ ସଂକ୍ରମଣର ସମ୍ଭାବନା କମ୍ ଥାଏ ଏବଂ କ୍ୱଚିତ୍ ଗଣ୍ଠି ଯନ୍ତ୍ରଣା, ଥକାପଣ, ଯକୃତ ସମସ୍ୟା, ଶୋଇବାରେ ଅସୁବିଧା ଓ ଚିନ୍ତାର କାରଣ ହୋଇପାରେ । ^[୧] ଗର୍ଭଧାରଣ ସମୟରେ କିମ୍ବା ସ୍ତନ୍ୟପାନ କରାଇବାଦ୍ୱାରା ଶିଶୁର କ୍ଷତି ହୁଏ ନାହିଁ ।^[୧] ଏହା ପ୍ରଥମ ପିଢୀର ଏକ ସେଫାଲୋସ୍ପୋରିନ୍ । ^[୩] ଏହା ଜୀବାଣୁ କୋଷ ପ୍ରାଚୀର ଗଠନର ଶେଷ ପର୍ଯ୍ୟାୟକୁ ପ୍ରତିରୋଧ କରିଥାଏ । ^[୪]

୧୯୬୭ ମସିହାରେ ସେଫାଡ୍ରକ୍ସିଲ୍ ପେଟେଣ୍ଟ୍ ହୋଇଥିଲା ଏବଂ ୧୯୭୮ରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା । ^[୫] ଏହା ଏକ ସାଧାରଣ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ । ^[୧] ଯୁକ୍ତରାଜ୍ୟରେ, ୨୦୨୧ ସୁଦ୍ଧା ଏହାର ଏକ କୋର୍ଷର ଖର୍ଚ୍ଚ ପାଖାପାଖି ୨୦ ପାଉଣ୍ଡ ହୁଏ । ^[୧] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ପରିମାଣ ପ୍ରାୟ ୧୦ ଡଲାର ଅଟେ। ^[୬]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ ^୧.୬ ^୧.୭ ^୧.୮ "5. Infection". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. p. 557. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)
↑ "A - Z Drug List from Drugs.com: Cefadroxil". Drugs.com (in ଇଂରାଜୀ). American Society of Health-System Pharmacists. Archived from the original on 24 May 2016. Retrieved 20 November 2021.
↑ Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (in ଇଂରାଜୀ) (15th ed.). New York: McGraw-Hill. p. 830. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-12-01.
↑ Jain, Mayur S.; Barhate, Shashikant D.; Gayakwad, Bhushan P. (22 March 2018). "Cefadroxil: A Review of Analytical Methods". Asian Journal of Pharmaceutical Analysis (in English). 8 (1): 58–61. doi:10.5958/2231-5675.2018.00011.X. Archived from the original on 2021-04-19. Retrieved 2021-12-01.{{cite journal}}: CS1 maint: unrecognized language (link)
↑ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 493. ISBN 9783527607495. Archived from the original on 2017-09-10. Retrieved 2020-12-31.
↑ "Cefadroxil Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 30 December 2021.

[BNF82-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ ^୧.୬ ^୧.୭ ^୧.୮ "5. Infection". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. p. 557. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)

[AHFS-2] "A - Z Drug List from Drugs.com: Cefadroxil". Drugs.com (in ଇଂରାଜୀ). American Society of Health-System Pharmacists. Archived from the original on 24 May 2016. Retrieved 20 November 2021.

[Katzung2021-3] Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (in ଇଂରାଜୀ) (15th ed.). New York: McGraw-Hill. p. 830. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-12-01.

[Jain2018-4] Jain, Mayur S.; Barhate, Shashikant D.; Gayakwad, Bhushan P. (22 March 2018). "Cefadroxil: A Review of Analytical Methods". Asian Journal of Pharmaceutical Analysis (in English). 8 (1): 58–61. doi:10.5958/2231-5675.2018.00011.X. Archived from the original on 2021-04-19. Retrieved 2021-12-01.{{cite journal}}: CS1 maint: unrecognized language (link)

[Fis2006-5] Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 493. ISBN 9783527607495. Archived from the original on 2017-09-10. Retrieved 2020-12-31.

[6] "Cefadroxil Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 30 December 2021.

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