ଆଜିଲସାର୍ଟନ

ଆଜିଲସାର୍ଟନ
Clinical data
Trade names	Edarbi, Azilva
Synonyms	Azilsartan medoxomil, TAK-536, TAK-491
AHFS/Drugs.com	monograph
MedlinePlus	a611028
data	US DailyMed: Azilsartan;
Routes of; administration	By mouth
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ; ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	60%
Metabolism	CYP2C9
Onset of action	Within 2 wks
Elimination half-life	11 hrs
Excretion	55% feces, 42% urine
Identifiers
	IUPAC name 2-Ethoxy-1-{[2'-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylic acid;
ECHA InfoCard	100.235.975
Chemical and physical data
Formula	C25H20N4O5
Molar mass	୪୫୬.୪୬ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)O;
	InChI InChI=InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32) ; Key:KGSXMPPBFPAXLY-UHFFFAOYSA-N ;
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ଆଜିଲସାର୍ଟନ, ଏକ ବେପାର ନାମ ଏଡାର୍ବି, ହେଉଛି ଉଚ୍ଚ ରକ୍ତଚାପର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ଏକ ଔଷଧ । ^[୨]^[୩] ଅନ୍ୟାନ୍ୟ ବ୍ୟବହାରରେ ମଧୁମେହ କିଡନୀ ରୋଗ ଏବଂ ହୃଦ୍‌ପାତ ଅନ୍ତର୍ଭୁକ୍ତ ହୋଇପାରେ । ^[୧] ଏହା ପାଟିରେ ଦିଆଯାଏ । ^[୧] ଔଷଧର ପ୍ରଭାବ ସାଧାରଣତଃ ୨ ସପ୍ତାହ ମଧ୍ୟରେ ଆରମ୍ଭ ହୁଏ । ^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ତରଳ ଝାଡ଼ା ଏବଂ ମୁଣ୍ଡ ବୁଲାଇବା ହୋଇପାରେ । ^[୨]^[୩] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆଞ୍ଜିଓଇଡିମା, ନିମ୍ନ ରକ୍ତଚାପ ଏବଂ ବୃକ୍‌କ ସମସ୍ୟା ଅନ୍ତର୍ଭୁକ୍ତ ହୋଇପାରେ। ^[୧] ଗର୍ଭାବସ୍ଥାରେ ବ୍ୟବହାର ଶିଶୁର କ୍ଷତି କରିପାରେ । ^[୪] ଏହା ଏକ ଆଞ୍ଜିଓଟେନସିନ୍ ୨ ରିସେପ୍ଟର ବ୍ଲକର୍ | ^[୨]

୨୦୧୧ ମସିହାରେ ଆମେରିକା ଏବଂ ୟୁରୋପରେ ଡାକ୍ତରୀ ବ୍ୟବହାର ପାଇଁ ଆଜିଲସାର୍ଟନ ଅନୁମୋଦିତ ହୋଇଥିଲା। ^[୨]^[୩] ଯୁକ୍ତରାଜ୍ୟରେ ଏହାର ୪ ସପ୍ତାହର ଖର୍ଚ୍ଚ ୨୦ ପାଉଣ୍ଡରୁ କମ ହୁଏ । ^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ପରିମାଣର ମୂଲ୍ୟ ପ୍ରାୟ ୧୬୦ ଡଲାର ଅଟେ । ^[୬]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ "Azilsartan Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 17 January 2022.
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "Edarbi- azilsartan kamedoxomil tablet". DailyMed. 26 July 2019. Archived from the original on 7 February 2019. Retrieved 9 March 2020.
↑ ^୩.୦ ^୩.୧ ^୩.୨ "Edarbi EPAR". European Medicines Agency (EMA). 18 May 2018. Archived from the original on 24 March 2020. Retrieved 9 March 2020.
↑ "Azilsartan medoxomil (Edarbi) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 26 November 2020. Retrieved 17 January 2022.
↑ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 189. ISBN 978-0857114105.
↑ "Azilsartan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 1 November 2016. Retrieved 17 January 2022.

[AHFS2022-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ "Azilsartan Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 17 January 2022.

[PI2022-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "Edarbi- azilsartan kamedoxomil tablet". DailyMed. 26 July 2019. Archived from the original on 7 February 2019. Retrieved 9 March 2020.

[EPAR2022-3] ୩.୦ ^୩.୧ ^୩.୨ "Edarbi EPAR". European Medicines Agency (EMA). 18 May 2018. Archived from the original on 24 March 2020. Retrieved 9 March 2020.

[4] "Azilsartan medoxomil (Edarbi) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 26 November 2020. Retrieved 17 January 2022.

[BNF81-5] BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 189. ISBN 978-0857114105.

[6] "Azilsartan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 1 November 2016. Retrieved 17 January 2022.

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