ଇକ୍ସେକିଜୁମାବ

ଇକ୍ସେକିଜୁମାବ
Monoclonal antibody
Type	Whole antibody
Source	Humanized
Target	Interleukin 17A (IL-17A)
Clinical data
Pronunciation	ix-ee-KIZ-ue-mab
Trade names	Taltz
AHFS/Drugs.com	monograph
MedlinePlus	a616025
data	EU EMA: yes; US DailyMed: Ixekizumab;
Pregnancy; category	AU: C ; US: N (Not classified yet) ; ;
Routes of; administration	Subcutaneous injection
Legal status
Legal status	AU: S4 (Prescription only) ; UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ; ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	54–90%
Metabolism	Presumably proteolysis
Elimination half-life	13 days
Chemical and physical data
Formula	C6492H10012N1728O2028S46
Molar mass	୧,୪୬,୧୯୨.୩୪ g·mol−1
(verify)

ଇକ୍ସେକିଜୁମାବ (ଇଂରାଜୀ ଭାଷାରେ Ixekizumab), ଟାଲ୍ଟଜ୍ ଏହାର ଏକ ବିକ୍ରୟ ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା ସୋରିଆସିସ, ସୋରିଆଟିକ୍ ଗଣ୍ଠି ପ୍ରଦାହ ଏବଂ ଆଙ୍କିଲୋଜିଙ୍ଗ ସ୍ପଣ୍ଡିଲାଇଟିସ ରୋଗମାନଙ୍କର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୩] ^[୫] ପ୍ଲେକ୍ ସୋରିଆସିସ ରୋଗରେ ଏହା ମଧ୍ୟମରୁ ଗମ୍ଭୀର ଅବସ୍ଥା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୩] ଏହା ଚର୍ମ ତଳେ ଏକ ଇଞ୍ଜେକସନ ଆକାରରେ ଦିଆଯାଏ ।^[୩]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଶ୍ୱାସନଳୀ ସଂକ୍ରମଣ ଏବଂ ଇଞ୍ଜେକସନ ନେଇଥିବା ସ୍ଥାନରେ ଯନ୍ତ୍ରଣା ହୋଇପାରେ ।^[୩] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ସଂକ୍ରମଣ ଏବଂ ଆଲର୍ଜ ଅନ୍ତର୍ଭୁକ୍ତ ହୋଇପାରେ ।^[୫] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ ।^[୬] ଏହା ଏକ ମୋନୋକ୍ଲୋନାଲ ଆଣ୍ଟିବଡି ଯାହା ଇଣ୍ଟରଲିଉକିନ୍ ୧୭ଏ (17A) ସ‌‌ହିତ ସଂଲଗ୍ନ ହୁଏ ଓ ତାକୁ ଅବରୋଧ କରି ପ୍ରଦାହକୁ ହ୍ରାସ କରେ ।^[୩]

୨୦୧୬ ମସିହାରେ ୟୁରୋପ ଏବଂ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ପାଇଁ ଇକ୍ସେକିଜୁମାବ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୫] ^[୩] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ୮୦ ମିଗ୍ରା ମାତ୍ରାର ମୂଲ୍ୟ ପ୍ରାୟ ୧,୧୩୦ ପାଉଣ୍ଡ ଥିଲା ।^[୭] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ରାଶିର ମୂଲ୍ୟ ପ୍ରାୟ ୬,୨୫୦ ଡଲାର ଅଟେ ।^[୮]

ଆଧାର

↑ ^୧.୦ ^୧.୧ "Ixekizumab (Taltz) Use During Pregnancy". Drugs.com. 27 November 2019. Archived from the original on 27 March 2020. Retrieved 27 March 2020.
↑ "12 Difficult-to-Pronounce Drug Names". Pharmacy Times. 7 February 2018. Archived from the original on 21 March 2018. Retrieved 22 March 2018.
↑ ^୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ ^୩.୪ ^୩.୫ ^୩.୬ "Taltz EPAR". European Medicines Agency (EMA). 2 May 2016. Archived from the original on 27 March 2020. Retrieved 27 March 2020.
↑ "Taltz 80 mg solution for injection in pre-filled syringe - Summary of Product Characteristics (SmPC)". (emc). 21 August 2019. Archived from the original on 27 March 2020. Retrieved 27 March 2020.
↑ ^୫.୦ ^୫.୧ ^୫.୨ "Ixekizumab Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 4 March 2021. Retrieved 26 November 2021.
↑ "Ixekizumab (Taltz) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 27 March 2020. Retrieved 1 December 2021.
↑ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1302. ISBN 978-0857114105.
↑ "Taltz Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 16 January 2021. Retrieved 1 December 2021.

[Drugs.com_pregnancy-1] ୧.୦ ^୧.୧ "Ixekizumab (Taltz) Use During Pregnancy". Drugs.com. 27 November 2019. Archived from the original on 27 March 2020. Retrieved 27 March 2020.

[2] "12 Difficult-to-Pronounce Drug Names". Pharmacy Times. 7 February 2018. Archived from the original on 21 March 2018. Retrieved 22 March 2018.

[EPAR2021-3] ୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ ^୩.୪ ^୩.୫ ^୩.୬ "Taltz EPAR". European Medicines Agency (EMA). 2 May 2016. Archived from the original on 27 March 2020. Retrieved 27 March 2020.

[4] "Taltz 80 mg solution for injection in pre-filled syringe - Summary of Product Characteristics (SmPC)". (emc). 21 August 2019. Archived from the original on 27 March 2020. Retrieved 27 March 2020.

[AHFS2021-5] ୫.୦ ^୫.୧ ^୫.୨ "Ixekizumab Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 4 March 2021. Retrieved 26 November 2021.

[6] "Ixekizumab (Taltz) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 27 March 2020. Retrieved 1 December 2021.

[BNF81-7] BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1302. ISBN 978-0857114105.

[8] "Taltz Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 16 January 2021. Retrieved 1 December 2021.

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