ମାକ୍ରୋଗୋଲ

<span title="International nonproprietary name (INN): <nowiki>Mr. Ibrahem/Macrogol</nowiki>">Mr. Ibrahem/Macrogol
Clinical data
Trade names	MiraLax, ClearLax, Golytely, others
Other names	Polyethylene glycol (PEG), PEG 3350, PEG 4000, PEG 6000
AHFS/Drugs.com	Professional Drug Facts
MedlinePlus	a603032
License data	<abbr class="country-name" title="<nowiki>United States</nowiki>">US DailyMed: Polyethylene_glycol;
Pregnancy; </nowiki>; </nowiki>category	<abbr class="country-name" title="<nowiki>Australia</nowiki>">AU: B1;
Routes of; </nowiki>; </nowiki>administration	By mouth
Drug class	Osmotic laxative
Legal status
Legal status	<abbr class="country-name" title="<nowiki>United Kingdom</nowiki>">UK: P (Pharmacy medicines) / POM; <abbr class="country-name" title="<nowiki>United States</nowiki>">US: ℞-only / OTC; Rx-only / OTC;
Pharmacokinetic data
Bioavailability	None
Excretion	Faeces (100%)
Identifiers
	IUPAC name Poly(oxyethylene);
Chemical and physical data
Formula	H–(OCH2CH2)n–OH
Molar mass	Varies
	(what is this?) (verify)

ମାକ୍ରୋଗୋଲ
Clinical data
Trade names	MiraLax, ClearLax, Golytely, others
Synonyms	Polyethylene glycol (PEG), PEG 3350, PEG 4000, PEG 6000
AHFS/Drugs.com
MedlinePlus	a603032
data	US DailyMed: Polyethylene_glycol;
Pregnancy; category	AU: B1 ; ;
Routes of; administration	By mouth
Legal status
Legal status	UK: Pharmacy medicines / POM; US: ℞-only / OTC; Rx-only / OTC;
Pharmacokinetic data
Bioavailability	None
Excretion	Faeces (100%)
Identifiers
	IUPAC name Poly(oxyethylene);
Chemical and physical data
Formula	H–(OCH2CH2)n–OH
Molar mass	Varies
(verify)

ମାକ୍ରୋଗୋଲ, ଅନ୍ୟ ନାମ ପଲିଏଥିଲିନ୍ ଗ୍ଲାଇକଲ୍ (PEG), ଏକ ଔଷଧ ଯାହା ଶିଶୁ ଏବଂ ବୟସ୍କମାନଙ୍କରକୋଷ୍ଠକାଠିନ୍ୟର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୧] ଏହା ଏକ କୋଲୋନୋସ୍କୋପି କରିବା ପୂର୍ବରୁ ଅନ୍ତନଳୀକୁ ଖାଲି କରିବା ପାଇଁ ମଧ୍ୟ ବ୍ୟବହୃତ ହୁଏ ।^[୧] ଏହା ପାଟିରେ ଦିଆଯାଏ ।^[୧] ଏହି ଚିକିତ୍ସାର ଉପକାର ସାଧାରଣତଃ ତିନି ଦିନ ମଧ୍ୟରେ ମିଳେ ।^[୨] ଏହା କେବଳ ଦୁଇ ସପ୍ତାହ ପାଇଁ ବ୍ୟବ‌ହାର କରିବାକୁ ସୁପାରିଶ କରାଯାଏ ।^[୩]

ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଅନ୍ତନଳୀ ବାୟୁ ବୃଦ୍ଧି, ପେଟ ଯନ୍ତ୍ରଣା ଏବଂ ବାନ୍ତି ହୋଇପାରେ ।^[୧] କିଛି ବିରଳ କିନ୍ତୁ ଗମ୍ଭୀର ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଅସ୍ୱାଭାବିକ ହୃତ୍‌ସ୍ପନ୍ଦନ, ବାତ ଏବଂ ବୃକ୍‌କ ସମସ୍ୟା ହୋଇପାରେ ।^[୪] ଗର୍ଭାବସ୍ଥାରେ ବ୍ୟବହାର ନିରାପଦ ମନେହୁଏ ।^[୫]^[୧] ଏହାକୁ ଏକ ଅସମୋଟିକ ରେଚକ (laxative) ଶ୍ରେଣୀଭୁକ୍ତ କରାଯାଇଛି ।^[୨] ଏହା ମଳରେ ଜଳର ପରିମାଣ ବୃଦ୍ଧି କରି କାମ କରେ ।^[୩]

୧୯୮୦ ମସିହାରେ ମାକ୍ରୋଗଲ୍ ଏକ ଅନ୍ତନଳୀ ସ‌ଫା କରିବା ପାଇଁ ବ୍ୟବହୃତ ହୋଇଥିଲା ଏବଂ ୧୯୯୯ରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୬] ^[୭] ^[୮] ଏହା ଏକ ନିଜସ୍ୱ ନାମରେ ଦୋକାନରେ ଉପଲବ୍ଧ ହୁଏ ।^[୧] ^[୯] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୧୯ ସୁଦ୍ଧା ଏହାର ଡୋଜ ପିଛା ମୂଲ୍ୟ £୦.୧୪ ରହିଛି ।^[୧] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ପରିମାଣର ହୋଲସେଲ ମୂଲ୍ୟ ପ୍ରାୟ $୧.୪୦ ଅଟେ ।^[୧୦] ୨୦୧୭ ମସିହାରେ, ଏହା ଆମେରିକାରେ ୧୬୨ତମ ସାଧାରଣ ପ୍ରେସକ୍ରିପସନ ଔଷଧ ଥିଲା, ଯେଉଁଥିରେ ତିନି ଲକ୍ଷରୁ ଅଧିକ ପ୍ରେସକ୍ରିପସନ୍ ରହିଥିଲା । ^[୧୧] ^[୧୨] ସାଧାରଣତଃ ଏହା ଇଲେକ୍ଟ୍ରୋଲାଇଟ୍ ସହିତ ଏକତ୍ର ପ୍ରସ୍ତୁତ କରାଯାଏ ।^[୧୩]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ ^୧.୬ British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 57–58. ISBN 9780857113382.
↑ ^୨.୦ ^୨.୧ "DailyMed - polyethylene glycol 3350 powder, for solution". dailymed.nlm.nih.gov. Archived from the original on 26 April 2021. Retrieved 19 April 2019.
↑ ^୩.୦ ^୩.୧ "Polyethylene Glycol 3350: MedlinePlus Drug Information". medlineplus.gov (in ଇଂରାଜୀ). Archived from the original on 27 April 2021. Retrieved 19 April 2019.
↑ "PEG-3350 and Electrolytes for Oral Solution" (PDF). FDA. Archived from the original (PDF) on 30 August 2017. Retrieved 19 April 2019.
↑ "Polyethylene glycol 3350 Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 April 2021. Retrieved 19 April 2019.
↑ Townsend, Courtney M.; Beauchamp, R. Daniel; Evers, B. Mark; Mattox, Kenneth L. (2016). Sabiston Textbook of Surgery E-Book: The Biological Basis of Modern Surgical Practice (in ଇଂରାଜୀ). Elsevier Health Sciences. p. 1325. ISBN 9780323401630. Archived from the original on 2021-04-30. Retrieved 2020-05-22.
↑ "Prescription Polyethylene Glycol 3350; Denial of a Hearing and Order Withdrawing Approval of Abbreviated New Drug Applications". Federal Register. 2 April 2018. Archived from the original on 28 April 2021. Retrieved 19 April 2019.
↑ Ginsberg, Gregory G.; Kochman, Michael L.; Norton, Ian D.; Gostout, Christopher J. (2011). Clinical Gastrointestinal Endoscopy E-Book: Expert Consult - Online and Print (in ଇଂରାଜୀ). Elsevier Health Sciences. p. 87. ISBN 9781437735703. Archived from the original on 2021-04-30. Retrieved 2020-05-22.
↑ "Polyethylene glycol 3350 Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 April 2021. Retrieved 19 April 2019.
↑ "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services (in ଇଂରାଜୀ). Archived from the original on 2019-03-06. Retrieved 3 March 2019.
↑ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
↑ "Polyethylene Glycol 3350 - Drug Usage Statistics". ClinCalc. Archived from the original on 3 March 2021. Retrieved 11 April 2020.
↑ Aronson, Jeffrey K. (2015). Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (in ଇଂରାଜୀ). Elsevier. p. 567. ISBN 9780444537164. Archived from the original on 2021-04-30. Retrieved 2020-05-22.

[BNF76-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ ^୧.୬ British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 57–58. ISBN 9780857113382.

[Daily2019-2] ୨.୦ ^୨.୧ "DailyMed - polyethylene glycol 3350 powder, for solution". dailymed.nlm.nih.gov. Archived from the original on 26 April 2021. Retrieved 19 April 2019.

[Pub2019-3] ୩.୦ ^୩.୧ "Polyethylene Glycol 3350: MedlinePlus Drug Information". medlineplus.gov (in ଇଂରାଜୀ). Archived from the original on 27 April 2021. Retrieved 19 April 2019.

[4] "PEG-3350 and Electrolytes for Oral Solution" (PDF). FDA. Archived from the original (PDF) on 30 August 2017. Retrieved 19 April 2019.

[Preg2019-5] "Polyethylene glycol 3350 Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 April 2021. Retrieved 19 April 2019.

[6] Townsend, Courtney M.; Beauchamp, R. Daniel; Evers, B. Mark; Mattox, Kenneth L. (2016). Sabiston Textbook of Surgery E-Book: The Biological Basis of Modern Surgical Practice (in ଇଂରାଜୀ). Elsevier Health Sciences. p. 1325. ISBN 9780323401630. Archived from the original on 2021-04-30. Retrieved 2020-05-22.

[7] "Prescription Polyethylene Glycol 3350; Denial of a Hearing and Order Withdrawing Approval of Abbreviated New Drug Applications". Federal Register. 2 April 2018. Archived from the original on 28 April 2021. Retrieved 19 April 2019.

[8] Ginsberg, Gregory G.; Kochman, Michael L.; Norton, Ian D.; Gostout, Christopher J. (2011). Clinical Gastrointestinal Endoscopy E-Book: Expert Consult - Online and Print (in ଇଂରାଜୀ). Elsevier Health Sciences. p. 87. ISBN 9781437735703. Archived from the original on 2021-04-30. Retrieved 2020-05-22.

[MTM2019-9] "Polyethylene glycol 3350 Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 April 2021. Retrieved 19 April 2019.

[NADAC2019-10] "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services (in ଇଂରାଜୀ). Archived from the original on 2019-03-06. Retrieved 3 March 2019.

[ref-11] "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.

[ref1-12] "Polyethylene Glycol 3350 - Drug Usage Statistics". ClinCalc. Archived from the original on 3 March 2021. Retrieved 11 April 2020.

[13] Aronson, Jeffrey K. (2015). Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (in ଇଂରାଜୀ). Elsevier. p. 567. ISBN 9780444537164. Archived from the original on 2021-04-30. Retrieved 2020-05-22.

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