ବେଲିମୁମାବ

ବେଲିମୁମାବ
	Fab fragment of belimumab. ଛାଞ୍ଚ:PDB.
Monoclonal antibody
Type	Whole antibody
Source	Human
Target	B-cell activating factor (BAFF, BLyS)
Clinical data
Trade names	Benlysta
Synonyms	LymphoStat-B
AHFS/Drugs.com	monograph
MedlinePlus	a611027
data	EU EMA: yes; US DailyMed: Belimumab;
Pregnancy; category	AU: C ; US: N (Not classified yet) ; ;
Routes of; administration	Intravenous
Legal status
Legal status	US: ℞-only ; EU: Rx-only ;
Chemical and physical data
Formula	C6714H10428O2102S52
Molar mass	୧,୨୬,୪୫୦.୩0 g·mol−1
(verify)

ବେଲିମୁମାବ, ବେପାର ନାମ ବେନିଷ୍ଟା, ଏକ ଔଷଧ ଯାହା ସିଷ୍ଟମିକ୍ ଲୁପୁସ୍ ଏରିଥେମାଟୋସ୍ (SLE) କିମ୍ବା ଲୁପୁସ ବୃକ୍‌କ ପ୍ରଦାହ ରୋଗର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୪] ଏହା ଅନ୍ୟାନ୍ୟ ଚିକିତ୍ସା ସ‌ହିତ ଏହା ବ୍ୟବହୃତ ହୁଏ, ଯେତେବେଳେ ସେଗୁଡ଼ିକ ପର୍ଯ୍ୟାପ୍ତ ନୁହେଁ । ^[୫] ଏହା ଏକ ଶିରାରେ କିମ୍ବା ଚର୍ମ ତଳେ ଇଞ୍ଜେକ୍ସନ ଆକାରରେ ଦିଆଯାଏ |।^[୩]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଶ୍ୱାସନଳୀ ସଂକ୍ରମଣ, ତରଳ ଝଡ଼ା ଏବଂ ହର୍ପିସ ଜୋଷ୍ଟର ହୋଇପାରେ । ^[୬] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଇନଫ୍ୟୁଜନ୍ ପ୍ରତିକ୍ରିୟା, ପ୍ରଗତିଶୀଳ ମଲ୍ଟିଫୋକାଲ୍ ଲ୍ୟୁକୋଏନସେଫାଲୋପାଥି, ଅବସାଦ ଏବଂ ଆନାଫାଇଲକ୍ସିସ୍ ହୋଇପାରେ । ^[୨] ^[୪] ଏହା ଏକ ମୋନୋକ୍ଲୋନାଲ ଆଣ୍ଟିବଡି ବି-ସେଲ୍ ଆକ୍ଟିଭିଟିଙ୍ଗ୍ ଫ୍ୟାକ୍ଟର୍ (BAFF)କୁ ମଧ୍ୟ ସଂଲଗ୍ନ ଓ ଅବରୋଧ କରି ବି- ଲିମ୍ଫୋସାଇଟ‌ର ଆୟୁଷକୁ ହ୍ରାସ କରେ । ^[୨]

୨୦୧୧ରେ ଆମେରିକା ଏବଂ ୟୁରୋପରେ ଡାକ୍ତରୀ ବ୍ୟବହାର ପାଇଁ ବେଲିମୁମାବକୁ ଅନୁମୋଦନ କରାଯାଇଥିଲା। ^[୬] ^[୪] ^[୫] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ଏହାର ୪୦୦ ମିଗ୍ରାର ମୂଲ୍ୟ ପ୍ରାୟ ୪୦୫ ଡଲାର ଅଟେ। । ^[୭]

ଆଧାର

↑ ^୧.୦ ^୧.୧ "Belimumab (Benlysta) Use During Pregnancy". Drugs.com. 5 February 2020. Archived from the original on 4 December 2020. Retrieved 29 July 2020.
↑ ^୨.୦ ^୨.୧ ^୨.୨ "Benlysta EPAR". European Medicines Agency (EMA). Archived from the original on 25 October 2020. Retrieved 29 July 2020.
↑ ^୩.୦ ^୩.୧ "Benlysta- belimumab injection, powder, lyophilized, for solution Benlysta- belimumab solution". DailyMed. 17 January 2020. Archived from the original on 25 September 2020. Retrieved 29 July 2020.
↑ ^୪.୦ ^୪.୧ ^୪.୨ "Benlysta- belimumab injection, powder, lyophilized, for solution Benlysta- belimumab solution". DailyMed. 17 January 2020. Archived from the original on 25 September 2020. Retrieved 29 July 2020.
↑ ^୫.୦ ^୫.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 891. ISBN 978-0857114105.
↑ ^୬.୦ ^୬.୧ "Benlysta EPAR". European Medicines Agency (EMA). Archived from the original on 25 October 2020. Retrieved 29 July 2020.
↑ "Benlysta Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Retrieved 8 January 2022.

[autogen1-1] ୧.୦ ^୧.୧ "Belimumab (Benlysta) Use During Pregnancy". Drugs.com. 5 February 2020. Archived from the original on 4 December 2020. Retrieved 29 July 2020.

[autogen2-2] ୨.୦ ^୨.୧ ^୨.୨ "Benlysta EPAR". European Medicines Agency (EMA). Archived from the original on 25 October 2020. Retrieved 29 July 2020.

[autogen3-3] ୩.୦ ^୩.୧ "Benlysta- belimumab injection, powder, lyophilized, for solution Benlysta- belimumab solution". DailyMed. 17 January 2020. Archived from the original on 25 September 2020. Retrieved 29 July 2020.

[PI2022-4] ୪.୦ ^୪.୧ ^୪.୨ "Benlysta- belimumab injection, powder, lyophilized, for solution Benlysta- belimumab solution". DailyMed. 17 January 2020. Archived from the original on 25 September 2020. Retrieved 29 July 2020.

[BNF81-5] ୫.୦ ^୫.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 891. ISBN 978-0857114105.

[EPAR2022-6] ୬.୦ ^୬.୧ "Benlysta EPAR". European Medicines Agency (EMA). Archived from the original on 25 October 2020. Retrieved 29 July 2020.

[7] "Benlysta Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Retrieved 8 January 2022.

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