ପିଟୋଲିସାଣ୍ଟ

ପିଟୋଲିସାଣ୍ଟ
Clinical data
Trade names	Wakix, Ozawade, others
Synonyms	Tiprolisant; Ciproxidine; BF2.649
AHFS/Drugs.com	monograph
MedlinePlus	a619055
data	EU EMA: yes; US DailyMed: Pitolisant;
Routes of; administration	By mouth
Legal status
Legal status	US: ℞-only ; EU: Rx-only ;
Identifiers
	IUPAC name 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine;
Chemical and physical data
Formula	C17H26ClNO
Molar mass	୨୯୫.୮୫ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl;
	InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2 ; Key:NNACHAUCXXVJSP-UHFFFAOYSA-N ;
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ଇଂରାଜୀ ଲିଙ୍କ

https://or.wikipedia.org/wiki/Pitolisant

ପିଟୋଲିସାଣ୍ଟ, ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ଏକ ବେପାର ନାମ ୱାକିକ୍ସ, ହେଉଛି ଏକ ଔଷଧ ଯାହା ନାର୍କୋଲପ୍ସିରେ ହେଉଥିବା ଅତ୍ୟଧିକ ଦିବା ନିଦ୍ରାର ଚିକିତ୍ସା ପାଇଁ ଦିଆଯାଏ ।^[୩] ଏହାକୁ ସକାଳେ ଦିନରେ ଥରେ ପାଟିରେ ଦିଆଯାଏ ।^[୨] ^[୪]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମୁଣ୍ଡବିନ୍ଧା, ଶୋଇବାରେ ଅସୁବିଧା, ବାନ୍ତି ଏବଂ ଉଦ୍‌ବେଗ ହୋଇପାରେ ।^[୨] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ କ୍ୟୁଟି ପ୍ରଲମ୍ବିତ ହୋଇପାରେ ।^[୫] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ ।^[୬] ଏହା ହିଷ୍ଟାମାଇନ୍ ଏଚ_୩ ରିସେପ୍ଟରର ହେଉଥିବା ସାଧାରଣପ୍ରତିକ୍ରିୟାର ଏକ ବିପରୀତ ପ୍ରତିକ୍ରିୟା ଆଣେ ।^[୩] ଏହା ମସ୍ତିଷ୍କରେ ହିଷ୍ଟାମାଇନ୍ ନ୍ୟୁରନ୍ ଗୁଡିକର କାର୍ଯ୍ୟକଳାପକୁ ବୃଦ୍ଧି କରାଇଥାଏ, ଯାହା ଜଣେ ବ୍ୟକ୍ତିଙ୍କୁ ଜାଗ୍ରତ କରିଥାଏ | ^[୭] ^[୨]

୨୦୧୯ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ର ଏବଂ ୨୦୨୧ରେ ୟୁରୋପରେ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ପାଇଁ ପିଟୋଲିସାଣ୍ଟ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୫] ^[୨] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ଏହା ନିମନ୍ତେ ପ୍ରତି ମାସରେ ପ୍ରାୟ ୩୧୦ ପାଉଣ୍ଡ ଖର୍ଚ୍ଚ ହୁଏ ।^[୪] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ରାଶିର ମୁଲ୍ୟ ପ୍ରାୟ ୬,୮୦୦ ଡଲାର ଅଟେ । ^[୮]

ଆଧାର

↑ "Wakix EPAR". European Medicines Agency (EMA). Archived from the original on 12 November 2020. Retrieved 18 August 2020. Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ "Ozawade EPAR". European Medicines Agency (EMA). Archived from the original on 15 October 2021. Retrieved 15 October 2021.
↑ ^୩.୦ ^୩.୧ ^୩.୨ "Wakix- pitolisant hydrochloride tablet, film coated". DailyMed. 6 November 2019. Archived from the original on 11 August 2020. Retrieved 18 August 2020.
↑ ^୪.୦ ^୪.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 513. ISBN 978-0857114105.
↑ ^୫.୦ ^୫.୧ "Pitolisant Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 28 October 2021.
↑ "Pitolisant (Wakix) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 18 March 2020. Retrieved 28 October 2021.
↑ Syed YY (20 July 2016). "Pitolisant: First Global Approval". Drugs. 76 (13): 1313–1318. doi:10.1007/s40265-016-0620-1. PMID 27438291.
↑ "Wakix Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 24 January 2021. Retrieved 28 October 2021.

[Wakix_EPAR-1] "Wakix EPAR". European Medicines Agency (EMA). Archived from the original on 12 November 2020. Retrieved 18 August 2020. Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged.

[EPAR2021-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ "Ozawade EPAR". European Medicines Agency (EMA). Archived from the original on 15 October 2021. Retrieved 15 October 2021.

[PI2021-3] ୩.୦ ^୩.୧ ^୩.୨ "Wakix- pitolisant hydrochloride tablet, film coated". DailyMed. 6 November 2019. Archived from the original on 11 August 2020. Retrieved 18 August 2020.

[BNF81-4] ୪.୦ ^୪.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 513. ISBN 978-0857114105.

[AHFS2021-5] ୫.୦ ^୫.୧ "Pitolisant Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 28 October 2021.

[6] "Pitolisant (Wakix) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 18 March 2020. Retrieved 28 October 2021.

[Syed2016-7] Syed YY (20 July 2016). "Pitolisant: First Global Approval". Drugs. 76 (13): 1313–1318. doi:10.1007/s40265-016-0620-1. PMID 27438291.

[8] "Wakix Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 24 January 2021. Retrieved 28 October 2021.

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