ରିମେଗେପାଣ୍ଟ

ରିମେଗେପାଣ୍ଟ
Clinical data
Trade names	Nurtec ODT, Vydura
Synonyms	BHV-3000, BMS-927711
AHFS/Drugs.com	monograph
MedlinePlus	a620031
data	US DailyMed: Rimegepant;
Routes of; administration	By mouth
Legal status
Legal status	US: ℞-only ;
Pharmacokinetic data
Onset of action	With 2 hr
Duration of action	48 hr
Identifiers
	IUPAC name [(5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate;
Chemical and physical data
Formula	C28H28F2N6O3
Molar mass	୫୩୪.୫୭ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC(C2=C(C=CC=N2)C(C1C3=C(C(=CC=C3)F)F)N)OC(=O)N4CCC(CC4)N5C6=C(NC5=O)N=CC=C6;
	InChI InChI=1S/C28H28F2N6O3/c29-20-6-1-4-17(23(20)30)18-8-9-22(25-19(24(18)31)5-2-12-32-25)39-28(38)35-14-10-16(11-15-35)36-21-7-3-13-33-26(21)34-27(36)37/h1-7,12-13,16,18,22,24H,8-11,14-15,31H2,(H,33,34,37)/t18-,22+,24-/m0/s1; Key:KRNAOFGYEFKHPB-ANJVHQHFSA-N;

ରିମେଗେପାଣ୍ଟ, ଏକ ବେପାର ନାମ ନୁର୍ଟେକ ଓଡିଟି (Nurtec ODT), ହେଉଛି ଏକ ଔଷଧ ଯାହା ଅଧକପାଳି ରୋଗର ଚିକିତ୍ସା ତଥା ପ୍ରତିରୋଧ ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୨] ଏହା ପାଟିରେ ଦିଆଯାଏ ।^[୩] ଔଷଧର ପ୍ରଭାବ ଦୁଇ ଘଣ୍ଟା ମଧ୍ୟରେ ଆରମ୍ଭ ହୋଇ ୪୮ ଘଣ୍ଟା ପର୍ଯ୍ୟନ୍ତ ରହିପାରେ ।^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଅଇ ଓ ପେଟ ଯନ୍ତ୍ରଣା ହୋଇପାରେ ।^[୨] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆଲର୍ଜି ପ୍ରତିକ୍ରିୟା ହୋଇପାରେ ।^[୨] ଗର୍ଭଧାରଣ ଏବଂ ସ୍ତନ୍ୟପାନରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ ।^[୪] ଏହା ସିଜିଆରପି (CGRP) ରିସେପ୍ଟରକୁ ଅବରୋଧ କରି କାର୍ଯ୍ୟକ୍ଷମ ହୁଏ ।^[୩]

୨୦୨୦ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ରିମେଗେପାଣ୍ଟ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୩] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହାର ଏକ ମାତ୍ରାର ମୂଲ୍ୟ ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ ୧୨୦ ଡଲାର ଥିଲା ।^[୫] ୨୦୨୧ ସୁଦ୍ଧା ଏହା ୟୁରୋପ କିମ୍ବା ବ୍ରିଟେନରେ ଅନୁମୋଦିତ ହୋଇନାହିଁ ।^[୬]

ଆଧାର

1 2 3 Skidmore-Roth, Linda (1 April 2021). Mosby's Drug Guide for Nursing Students with 2022 Update - E-Book (in ଇଂରାଜୀ). Elsevier Health Sciences. p. 1218. ISBN 978-0-323-87656-8. Archived from the original on 17 October 2021. Retrieved 17 October 2021.
1 2 3 "Nurtec ODT - rimegepant sulfate tablet, orally disintegrating". DailyMed. 19 February 2020. Archived from the original on 28 November 2020. Retrieved 19 March 2020.
1 2 3 "Rimegepant Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 17 October 2021.
↑ "Rimegepant (Nurtec ODT) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Retrieved 17 October 2021.
↑ "Nurtec ODT Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 7 June 2021. Retrieved 17 October 2021.
↑ "Rimegepant". SPS - Specialist Pharmacy Service. 5 October 2017. Archived from the original on 17 October 2021. Retrieved 17 October 2021.

[Skid2021-1] 1 2 3 Skidmore-Roth, Linda (1 April 2021). Mosby's Drug Guide for Nursing Students with 2022 Update - E-Book (in ଇଂରାଜୀ). Elsevier Health Sciences. p. 1218. ISBN 978-0-323-87656-8. Archived from the original on 17 October 2021. Retrieved 17 October 2021.

[PI2021-2] 1 2 3 "Nurtec ODT - rimegepant sulfate tablet, orally disintegrating". DailyMed. 19 February 2020. Archived from the original on 28 November 2020. Retrieved 19 March 2020.

[AHFS2021-3] 1 2 3 "Rimegepant Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 17 October 2021.

[4] "Rimegepant (Nurtec ODT) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Retrieved 17 October 2021.

[5] "Nurtec ODT Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 7 June 2021. Retrieved 17 October 2021.

[6] "Rimegepant". SPS - Specialist Pharmacy Service. 5 October 2017. Archived from the original on 17 October 2021. Retrieved 17 October 2021.

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