ବେଜଲୋଟୋକ୍ସୁମାବ

ବେଜଲୋଟୋକ୍ସୁମାବ
Monoclonal antibody
Type	Whole antibody
Source	Human
Target	Clostridium difficile toxin B
Clinical data
Trade names	Zinplava
AHFS/Drugs.com	monograph
MedlinePlus	a617003
data	EU EMA: yes; US DailyMed: Bezlotoxumab;
Pregnancy; category	AU: B2 ; ;
Routes of; administration	Intravenous
ATC code	J06BC03 (WHO) ;
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ;
Identifiers
CAS Number	1246264-45-8;
DrugBank	DB13140;
ChemSpider	none;
UNII	4H5YMK1H2E;
KEGG	D10453 ;
Chemical and physical data
Formula	C6464H9974N1726O2014S46
Molar mass	୧,୪୫,୫୬୫.୭୨ g·mol−1

ବେଜଲୋଟୋକ୍ସୁମାବ, ବିକ୍ରୟ ନାମ ଜିନପ୍ଲାଭା, ଏକ ଔଷଧ ଯାହା କ୍ଲୋଷ୍ଟ୍ରିଡିଅମ ଡିଫିସିଲ ସଂକ୍ରମଣରର ପୁନରାବୃତି ରୋକିବା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୧] ଆଣ୍ଟିବାୟୋଟିକ୍ ସହିତ ଏହା ବ୍ୟବହୃତ ହୁଏ । ^[୨] ଏହା ଏକ ଶିରାରେ ଇଞ୍ଜେକ୍ସନ ଆକାରରେ ଦିଆଯାଏ । ^[୨]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ବାନ୍ତି, ତରଳ ଝାଡ଼ା, ଜ୍ୱର ଏବଂ ମୁଣ୍ଡବିନ୍ଧା ଅନ୍ତର୍ଭୁକ୍ତ ହୋଇପାରେ । ^[୧] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ହୃଦ୍‌ପାତ ହୋଇପାରେ । ^[୩] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ | ^[୪] ଏହା ଏକ ମୋନୋକ୍ଲୋନାଲ ଆଣ୍ଟିବଡି ଯାହା କ୍ଲୋଷ୍ଟ୍ରିଡିୟମ୍ ଡିଫାଇସିଲ ଟକ୍ସିନ ବି ସହିତ ଅନୁବନ୍ଧିତ ହୋଇଥାଏ । ^[୫]

୨୦୧୬ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏବଂ ୨୦୧୭ରେ ୟୁରୋପରେ ମେଡିକାଲ୍ ବ୍ୟବହାର ପାଇଁ ବେଜଲୋଟକ୍ସୁମାବ୍ ଅନୁମୋଦିତ ହୋଇଥିଲା । ^[୧] ^[୩] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହାର ଏକ ୧୦୦୦ମିଗ୍ରା ଭାଏଲ ମୂଲ୍ୟ ପ୍ରାୟ ୪,୦୦୦ ଡଲାର ଅଟେ । ^[୬]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ "Zinplava". Archived from the original on 9 January 2021. Retrieved 10 January 2022.
↑ ^୨.୦ ^୨.୧ "Zinplava". Archived from the original on 9 January 2021. Retrieved 10 January 2022.
↑ ^୩.୦ ^୩.୧ "DailyMed - ZINPLAVA- bezlotoxumab injection, solution". dailymed.nlm.nih.gov. Archived from the original on 11 August 2021. Retrieved 10 January 2022.
↑ "Bezlotoxumab (Zinplava) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 5 December 2020. Retrieved 10 January 2022.
↑ "DailyMed - ZINPLAVA- bezlotoxumab injection, solution". dailymed.nlm.nih.gov. Archived from the original on 11 August 2021. Retrieved 10 January 2022.
↑ "Zinplava Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 25 October 2021. Retrieved 10 January 2022.

[EPAR2022-1] ୧.୦ ^୧.୧ ^୧.୨ "Zinplava". Archived from the original on 9 January 2021. Retrieved 10 January 2022.

[autogen1-2] ୨.୦ ^୨.୧ "Zinplava". Archived from the original on 9 January 2021. Retrieved 10 January 2022.

[PI2022-3] ୩.୦ ^୩.୧ "DailyMed - ZINPLAVA- bezlotoxumab injection, solution". dailymed.nlm.nih.gov. Archived from the original on 11 August 2021. Retrieved 10 January 2022.

[4] "Bezlotoxumab (Zinplava) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 5 December 2020. Retrieved 10 January 2022.

[autogen3-5] "DailyMed - ZINPLAVA- bezlotoxumab injection, solution". dailymed.nlm.nih.gov. Archived from the original on 11 August 2021. Retrieved 10 January 2022.

[6] "Zinplava Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 25 October 2021. Retrieved 10 January 2022.

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