ଫିନାଷ୍ଟେରାଇଡ

ଉଇକିପିଡ଼ିଆ‌ରୁ
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ଫିନାଷ୍ଟେରାଇଡ
Finasteride.svg
Finasteride-3D-balls.png
Clinical data
Trade namesProscar, Propecia, others
SynonymsMK-906; YM-152; L-652,931; 17β-(N-tert-Butylcarbamoyl)-4-aza-5α-androst-1-en-3-one; N-(1,1-Dimethylethyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide
AHFS/Drugs.commonograph
MedlinePlusa698016
data
Pregnancy
category
  • X (will cause birth defects)
Routes of
administration
By mouth
Legal status
Legal status
Pharmacokinetic data
Bioavailability65%[୧]
Protein binding90%[୧]
MetabolismLiver (CYP3A4, ALDH)[୧]
Elimination half-lifeAdults: 5–6 hours[୧]
Elderly: >8 hours[୧]
ExcretionFeces: 57%[୧]
Urine: 40%[୧]
Identifiers
ECHA InfoCard100.149.445 Edit this at Wikidata
Chemical and physical data
FormulaC23H36N2O2
Molar mass୩୭୨.୫୫ g·mol−1
3D model (JSmol)
  (verify)

ଫିନାଷ୍ଟେରାଇଡ, ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ବିକ୍ରୟ ନାମ ପ୍ରୋସ୍କାର ଏବଂ ପ୍ରୋପେସିଆ, ଏକ ଔଷଧ ଯାହା ମୁଖ୍ୟତଃ ପୁରୁଷମାନଙ୍କ ମଧ୍ୟରେ ବର୍ଦ୍ଧିତ ପ୍ରୋଷ୍ଟେଟ୍ କିମ୍ବା କେଶହାନୀ ପାଇଁ ବ୍ୟବହୃତ ହୁଏ |[୨] ଏହା ମହିଳାମାନଙ୍କର ଅତ୍ୟଧିକ କେଶ ବୃଦ୍ଧି ପାଇଁ ଏବଂ ଟ୍ରାନ୍ସଜେଣ୍ଡର ମହିଳାଙ୍କର ହରମୋନ ଥେରାପିର ଏକ ଅଂଶ ଭାବରେ ମଧ୍ୟ ବ୍ୟବହାର କରାଯାଇପାରିବ | [୩] [୪] ଏହା ପାଟିରେ ଦିଆଯାଏ | [୫]

ଫିନଷ୍ଟେରାଇଡର ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟା ଅତି ବିରଳ,[୬] ତଥାପି କେତେକ ପୁରୁଷଙ୍କର ଯୌନ ଅସୁବିଧା, ଅବସାଦ ଏବଂ ସ୍ତନ ବୃଦ୍ଧି ଇପାରେ | [୭] [୮] କେତେକ ପୁରୁଷଙ୍କଠାରେ ଔଷଧ ବନ୍ଦ କରିବା ପରେ ମଧ୍ୟ ଯୌନ ଅସୁବିଧା ହୋଇପାରେ | [୯] [୧୦] ଏହା କେତେକ ପ୍ରକାରରପ୍ରୋଷ୍ଟେଟ କ୍ୟାନସରର ଆଶଙ୍କା ମଧ୍ୟ ବୃଦ୍ଧି କରିପାରେ |[୧୧] ଫିନାଷ୍ଟେରାଇଡ ହେଉଛି ୫α-ରିଡକ୍ଟେଜ ଇନହିବିଟର ଶ୍ରେଣୀର ଏକ ଔଷଧ ଏବଂ ସେଥିପାଇଁ ଏକ ଆଣ୍ଟିଆଣ୍ଡ୍ରୋଜେନ | [୧୨] ପ୍ରୋଷ୍ଟେଟ ଗ୍ରନ୍ଥି ଓ ସ୍କାଲ୍ପରେ ଏହା ଡିହାଇଡ୍ରୋଟେଷ୍ଟୋଷ୍ଟିରନ (DHT) ମାତ୍ରା ପ୍ରାୟ ୭୦% କମ୍ କରି ଏହା କାର୍ଯ୍ୟକ୍ଷମ ହୁଏ | [୨]

ଫିନଷ୍ଟେରାଇଡ ୧୯୮୪ ମସିହାରେ ପେଟେଣ୍ଟ୍ ହୋଇଥିଲା ଏବଂ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା ୧୯୯୨ ମସିହାରେ ।[୧୩] ଏହା ଏକ ସାଧାରଣ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ | [୧୪] ଏହା ମହଙ୍ଗା ନୁହେଁ | [୧୫] ଯୁକ୍ତରାଜ୍ୟରେ ଏକ ମାସ ଯୋଗାଣ ୨୦୧୯ ସୁଦ୍ଧା ପ୍ରତି ମାସରେ ୦.୯୦ ପା‌ଉଣ୍ଡ ଖର୍ଚ୍ଚ ହୋଇଥାଏ | [୧୬] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ, ଏହି ପରିମାଣର ହୋଲସେଲ ମୂଲ୍ୟ ପ୍ରାୟ ୨.୩୦ ଡଲାର ଅଟେ | [୧୭] ୨୦୧୭ ରେ, ଏହା ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୮୬ତମ ସାଧାରଣ ପ୍ରେସକ୍ରିପସନ ଔଷଧ ଥିଲା, ଯେଉଁଥିରେ ନଅ ଲକ୍ଷରୁ ଅଧିକ ପ୍ରେସକ୍ରିପସନ୍ ରହିଥିଲା | [୧୮] [୧୯]

ଆଧାର[ସମ୍ପାଦନା]

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