ପେଗଫିଲଗ୍ରାଷ୍ଟିମ

ପେଗଫିଲଗ୍ରାଷ୍ଟିମ
Clinical data
Trade names	Neulasta, Udenyca, Ristempa, others
Synonyms	pegfilgrastim-apgf, pegfilgrastim-bmez, pegfilgrastim-cbqv, pegfilgrastim-jmdb
AHFS/Drugs.com	monograph
MedlinePlus	a607058
data	EU EMA: yes; US DailyMed: Pegfilgrastim;
Pregnancy; category	AU: B3 ;
Routes of; administration	Subcutaneous
Legal status
Legal status	AU: S4 (Prescription only) ; UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ; ℞ (Prescription only);
Pharmacokinetic data
Elimination half-life	15–80 hrs
Identifiers
	IUPAC name N-(3-Hydroxypropyl)Methionylcolony-stimulating Factor (human), 1-Ether with .Alpha.-Methyl-.Omega.-Hydroxypoly(Oxyethylene);
ECHA InfoCard	100.169.155
Chemical and physical data
Formula	C845H1343N223O243S9
Molar mass	୧୮,୮୦୨.୯0 g·mol−1
(verify)

ଇଂରାଜୀ ଲିଙ୍କ

https://or.wikipedia.org/wiki/Pegfilgrastim

ପେଗଫିଲଗ୍ରାଷ୍ଟିମ, ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ନ୍ୟୁଲାଷ୍ଟା ଏକ ବିକ୍ରୟ ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା କେମୋଥେରାପି କିମ୍ବା ବିକିରଣ ରୋଗରେ କମ୍ ନିଉଟ୍ରୋଫିଲ ଥିଲେ ତାହାର ଚିକିତ୍ସା ନିମନ୍ତେ ବ୍ୟବହାର କରାଯାଏ ।^[୮] ^[୬] ଏହାର ଉପକାର ଫିଲଗ୍ରାଷ୍ଟିମ୍ ସହିତ ସମାନ କିନ୍ତୁ ବାରମ୍ବାର ଦିଆଯିବା ଆବଶ୍ୟକ ନୁହେଁ ।^[୮] ଚର୍ମ ତଳେ ଇଞ୍ଜେକସନ ଆକାରରେ ଦିଆଯାଏ ।^[୭]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ହାଡ଼ ଯନ୍ତ୍ରଣା ହୋଇପାରେ ।^[୭] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ପ୍ଲିହା ଫାଟିବା, ବୟସ୍କଙ୍କ ଶ୍ୱାସକ୍ରିୟା ସମସ୍ୟା ସିଣ୍ଡ୍ରୋମ (ADRS) ଏବଂ ଆନାଫାଇଲକ୍ସିସ୍ ହୋଇପାରେ ।^[୮] ଏହା ଫିଲଗ୍ରାଷ୍ଟିମର ଏକ ପେଗିଲେଟେଡ ଫର୍ମ, ଏକ ରେକମ୍ବିନାଣ୍ଟ ଗ୍ରାନୁଲୋସାଇଟ୍ କଲୋନୀ-ଉତ୍ତେଜକ କାରକ (GCSF) | ^[୬] ଏହା ଅସ୍ଥି ମଜ୍ଜାଦ୍ୱାରା ଶ୍ୱେତ ରକ୍ତ କଣିକା (ଲ୍ୟୁକୋସାଇଟ୍) ଉତ୍ପାଦନକୁ ବୃଦ୍ଧି କରିଥାଏ ^[୭]

୨୦୦୨ ମସିହାରେ ଆମେରିକା, ୟୁରୋପ ଏବଂ ଅଷ୍ଟ୍ରେଲିଆରେ ଡାକ୍ତରୀ ବ୍ୟବହାର ପାଇଁ ପେଗଫିଲଗ୍ରାଷ୍ଟିମ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୮] ^[୭] ^[୯] ଏହାର ନାମ ବିଶ୍ୱ ସ୍ୱାସ୍ଥ୍ୟ ସଂଗଠନର ଜରୁରୀ ଔଷଧ ତାଲିକାରେ ଅଛି ।^[୧୦] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୨୦୨୧ ସୁଦ୍ଧା ଏହାର ଏକ ମାତ୍ରା ପ୍ରାୟ ୬,୨୦୦ ଡଲାର ଅଟେ; ଯଦିଓ ଏକ ବାୟୋସିମିଲାର ପ୍ରତି ଡୋଜର ମୂଲ୍ୟ ୩,୮୦୦ ଡଲାର ।^[୧୧] ^[୧୨] ଯୁକ୍ତରାଜ୍ୟରେ ଏହି ରାଶିର ମୂଲ୍ୟ ମୂଲ୍ୟ ୪୧୦ ପାଉଣ୍ଡ ଅଟେ ।^[୧୩]

ଆଧାର

↑ Drugs.com International brand names for pegfilgrastim Archived 2016-04-22 at the Wayback Machine. Page accessed April 1, 2016
1 2 "Ziextenzo". Therapeutic Goods Administration (TGA). 13 December 2019. Archived from the original on 20 October 2021. Retrieved 25 August 2020.
↑ "Pegfilgrastim Use During Pregnancy". Drugs.com. 9 December 2019. Archived from the original on 5 December 2020. Retrieved 13 July 2020.
↑ "Neulasta Pre-Filled Syringe - Summary of Product Characteristics (SmPC)". (emc). 1 June 2021. Archived from the original on 15 January 2021. Retrieved 11 October 2021.
↑ "Neulasta On Body Injector - Summary of Product Characteristics (SmPC)". (emc). Archived from the original on 17 January 2021. Retrieved 11 October 2021.
1 2 3 "Neulasta- pegfilgrastim kit Neulasta- pegfilgrastim injection". DailyMed. Archived from the original on 15 July 2021. Retrieved 14 July 2021.
1 2 3 4 5 "Neulasta EPAR". European Medicines Agency (EMA). Archived from the original on 11 June 2020. Retrieved 2 April 2020.
1 2 3 4 "Pegfilgrastim Monograph for Professionals". Drugs.com. 22 August 2019. Archived from the original on 7 March 2016. Retrieved 11 June 2020.
↑ "NEULASTA pegfilgrastim rbe 6mg/0.6mL injection syringe with stelmi needle shield". Retrieved 27 October 2021.{{cite web}}: CS1 maint: url-status (link)
↑ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
↑ "Pegfilgrastim Prices, Coupons & Savings Tips - GoodRx". GoodRx.
↑ "Pegfilgrastim-Bmez Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 27 October 2021.
↑ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1078. ISBN 978-0857114105.

[generic-1] Drugs.com International brand names for pegfilgrastim Archived 2016-04-22 at the Wayback Machine. Page accessed April 1, 2016

[Ziextenzo_APM_summary-2] 1 2 "Ziextenzo". Therapeutic Goods Administration (TGA). 13 December 2019. Archived from the original on 20 October 2021. Retrieved 25 August 2020.

[Drugs.com_pregnancy-3] "Pegfilgrastim Use During Pregnancy". Drugs.com. 9 December 2019. Archived from the original on 5 December 2020. Retrieved 13 July 2020.

[4] "Neulasta Pre-Filled Syringe - Summary of Product Characteristics (SmPC)". (emc). 1 June 2021. Archived from the original on 15 January 2021. Retrieved 11 October 2021.

[5] "Neulasta On Body Injector - Summary of Product Characteristics (SmPC)". (emc). Archived from the original on 17 January 2021. Retrieved 11 October 2021.

[PI2021-6] 1 2 3 "Neulasta- pegfilgrastim kit Neulasta- pegfilgrastim injection". DailyMed. Archived from the original on 15 July 2021. Retrieved 14 July 2021.

[EPAR2021-7] 1 2 3 4 5 "Neulasta EPAR". European Medicines Agency (EMA). Archived from the original on 11 June 2020. Retrieved 2 April 2020.

[AHFS2021-8] 1 2 3 4 "Pegfilgrastim Monograph for Professionals". Drugs.com. 22 August 2019. Archived from the original on 7 March 2016. Retrieved 11 June 2020.

[9] "NEULASTA pegfilgrastim rbe 6mg/0.6mL injection syringe with stelmi needle shield". Retrieved 27 October 2021.{{cite web}}: CS1 maint: url-status (link)

[WHO23rd-10] World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

[11] "Pegfilgrastim Prices, Coupons & Savings Tips - GoodRx". GoodRx.

[12] "Pegfilgrastim-Bmez Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 27 October 2021.

[BNF81-13] BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1078. ISBN 978-0857114105.

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