ଆବାଟାସେପ୍ଟ

ଆବାଟାସେପ୍ଟ
Clinical data
Trade names	Orencia
AHFS/Drugs.com	monograph
MedlinePlus	a606016
data	EU EMA: yes; US DailyMed: Abatacept;
Pregnancy; category	AU: C ; US: N (Not classified yet) ; ;
Routes of; administration	Intravenous, subcutaneous
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ;
Pharmacokinetic data
Elimination half-life	13.1 days
Chemical and physical data
Formula	C3498H5458N922O1090S32
Molar mass	୭୮,୮୯୫.୪୩ g·mol−1
(verify)

ଆବାଟାସେପ୍ଟ, ଓରେନ୍ସିଆ ବ୍ରାଣ୍ଡ ନାମରେ ବିକ୍ରୟ, ଏକ ଔଷଧ ଯାହା ରିଉମାଟଏଡ ଆର୍ଥ୍ରାଇଟିସ, ଜୁଭେନାଇଲ ଇଡିଓପାଥିକ ଆର୍ଥ୍ରାଇଟିସ ଓ ସୋରିଆସିସ ଆର୍ଥ୍ରାଇଟିସ ରୋଗମାନଙ୍କ ଚିକିତ୍ସାରେ ଦିଆଯାଏ । ^[୨] ଏହା ଗ୍ରାଫ୍ଟ ବନାମ ହୋଷ୍ଟ ରୋଗ (GVHD) ରୋକିବା ପାଇଁ ମଧ୍ୟ ବ୍ୟବହୃତ ହୋଇପାରେ ।^[୩] ଏହା ସାଧାରଣତ a ଏକ ଶିରାରେ କିମ୍ବା ଚର୍ମ ତଳେ ଇଞ୍ଜେକ୍ସନ ଆକାରରେ ଦିଆଯାଏ । ^[୪] ଏହାର ମାତ୍ରା ଏବଂ ଅନ୍ତର ବ୍ୟକ୍ତିର ^[୩]ଶରୀରର ଓଜନ ଉପରେ ନିର୍ଭର କରେ । ^[୫]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଉର୍ଦ୍ଧ୍ୱ ଶ୍ୱାସନଳୀ ସଂକ୍ରମଣ, ମୁଣ୍ଡବିନ୍ଧା ଏବଂ ବାନ୍ତି ହୋଇପାରେ ।^[୨] ^[୩]ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆନାଫାଇଲାକ୍ସିସ୍ ଏବଂ ସଂକ୍ରମଣ ହୋଇପାରେ ।^[୩]ଏହା ସାଧାରଣତଃ ଗର୍ଭାବସ୍ଥାରେ ଦିଆଯାଏ ନାହିଁ; ଚିକିତ୍ସା ସମୟରେ ଏବଂ ପରବର୍ତ୍ତୀ ୧୪ ସପ୍ତାହ ପର୍ଯ୍ୟନ୍ତ ଜନ୍ମ ନିୟନ୍ତ୍ରଣକୁ ସୁପାରିଶ କରାଯାଏ । ^[୪] ଏହା ସିଡି୮୦(CD80) ଏବଂ ସିଡି୮୬ (CD86)କୁ ସଂଲଗ୍ନ ଓ ଅବରୋଧ କରିଟି ଜୀବକୋଷ ପ୍ରତିରକ୍ଷା କାର୍ଯ୍ୟକଳାପ କମେଇ କାର୍ଯ୍ୟକ୍ଷମ ହୁଏ । ^[୨]^[୬]

୨୦୦୫ ମସିହାରେ ଓ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏବଂ ୨୦୦୭ ମସିହାରେ ୟୁରୋପରେ ଡାକ୍ତରୀ ବ୍ୟବହାର ପାଇଁ ଆବାଟାସେପ୍ଟ ଅନୁମୋଦିତ ହୋଇଛି ।^[୨] ^[୩] ଯୁକ୍ତରାଷ୍ଟ୍ରର ଏହାର ମୂଲ୍ୟ ପ୍ରାୟ ୨,୬୦୦ରୁ ୫,୨୦୦ ଡଲାର ଅଟେ । ^[୭]

ଆଧାର

↑ "Orencia EPAR". European Medicines Agency (EMA). Archived from the original on 8 November 2021. Retrieved 6 October 2020. {{cite web}}: |archive-date= / |archive-url= timestamp mismatch; 30 ଅକ୍ଟୋବର 2021 suggested (help)
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "DailyMed - ORENCIA- abatacept injection, powder, lyophilized, for solution ORENCIA- abatacept injection, solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 12 January 2022.
↑ ^୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ ^୩.୪ "DailyMed - ORENCIA- abatacept injection, powder, lyophilized, for solution ORENCIA- abatacept injection, solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 12 January 2022.
↑ ^୪.୦ ^୪.୧ "10. Musculoskeletal system". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 1165–1166. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)
↑ "10. Musculoskeletal system". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 1165–1166. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)
↑ "Orencia EPAR". European Medicines Agency (EMA). Archived from the original on 8 November 2021. Retrieved 6 October 2020. {{cite web}}: |archive-date= / |archive-url= timestamp mismatch; 30 ଅକ୍ଟୋବର 2021 suggested (help)
↑ "Orencia Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 8 March 2016. Retrieved 9 November 2021.

[EPAR2022-1] "Orencia EPAR". European Medicines Agency (EMA). Archived from the original on 8 November 2021. Retrieved 6 October 2020. {{cite web}}: |archive-date= / |archive-url= timestamp mismatch; 30 ଅକ୍ଟୋବର 2021 suggested (help)

[PI2022-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "DailyMed - ORENCIA- abatacept injection, powder, lyophilized, for solution ORENCIA- abatacept injection, solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 12 January 2022.

[PI20222-3] ୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ ^୩.୪ "DailyMed - ORENCIA- abatacept injection, powder, lyophilized, for solution ORENCIA- abatacept injection, solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 12 January 2022.

[BNF82-4] ୪.୦ ^୪.୧ "10. Musculoskeletal system". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 1165–1166. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)

[autogen1-5] "10. Musculoskeletal system". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 1165–1166. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)

[autogen4-6] "Orencia EPAR". European Medicines Agency (EMA). Archived from the original on 8 November 2021. Retrieved 6 October 2020. {{cite web}}: |archive-date= / |archive-url= timestamp mismatch; 30 ଅକ୍ଟୋବର 2021 suggested (help)

[7] "Orencia Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 8 March 2016. Retrieved 9 November 2021.

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