ଲିଫିଟେଗ୍ରାଷ୍ଟ

ଲିଫିଟେଗ୍ରାଷ୍ଟ
Clinical data
Pronunciation	Xiidra /ˈzaɪdrə/
Trade names	Xiidra
Synonyms	SAR-1118
AHFS/Drugs.com	monograph
MedlinePlus	a616039
Pregnancy; category	AU: B1 ; US: N (Not classified yet) ; ;
Routes of; administration	Eye drops
Legal status
Legal status	AU: S4 (Prescription only) ; US: ℞-only ;
Identifiers
	IUPAC name N-{[2-(1-Benzofuran-6-ylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl}-3-(methylsulfonyl)-L-phenylalanine;
Chemical and physical data
Formula	C29H24Cl2N2O7S
Molar mass	୬୧୫.୪୮ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CS(=O)(=O)c1cccc(c1)C[C@@H](C(=O)O)NC(=O)c2c(cc3c(c2Cl)CCN(C3)C(=O)c4ccc5ccoc5c4)Cl;
	InChI InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1; Key:JFOZKMSJYSPYLN-QHCPKHFHSA-N;

ଇଂରାଜୀ ଲିଙ୍କ

https://or.wikipedia.org/wiki/Lifitegrast

ଲିଫିଟେଗ୍ରାଷ୍ଟ (ଇଂରାଜୀ ଭାଷାରେ Lifitegrast), ଜିଡ୍ରା (Xiidra) ଏହାର ଏକ ବେପାର ନାମ, ଶୁଷ୍କ ଚକ୍ଷୁର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ଏକ ଔଷଧ ।^[୨] ଏହାର ଲାଭ ଏହାର କ୍ଷତିଠାରୁ ଅଧିକ କି ନାହିଁ ତାହା ଅସ୍ପଷ୍ଟ ରହିଛି। ।^[୩] ^[୪] ଏହା ଆଖି ବୁନ୍ଦା ଭାବରେ ବ୍ୟବହୃତ ହୁଏ ।^[୨]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଅସ୍ପଷ୍ଟ ଦୃଷ୍ଟି, ନାଲି ଆଖି, ମୁଣ୍ଡବିନ୍ଧା, ସ୍ୱାଦର ପରିବର୍ତ୍ତନ ଏବଂ ଗଲୁ ହୋଇପାରେ ।^[୨] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ବିଷୟ ସ୍ପଷ୍ଟ ନୁହେଁ ।^[୫] ଏହାଟି ଜୀବକୋଷକୁ ପ୍ରତିରୋଧ କରି ପ୍ରଦାହ ହ୍ରାସ କରେ ।^[୩]

୨୦୧୬ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ପାଇଁ ଲିଫିଟେଗ୍ରାଷ୍ଟ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୨] ବ୍ରିଟେନ କିମ୍ବା ୟୁରୋପରେ ଏହା ଅନୁମୋଦିତ ନୁହେଁ ।^[୩] ^[୪] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହାର ମୂଲ୍ୟ ୨୦୨୧ ସୁଦ୍ଧା ମାସକୁ ଏହାର ଖର୍ଚ୍ଚ ପ୍ରାୟ ୫୮୦ ଡଲାର ।^[୬]

ଆଧାର[ସମ୍ପାଦନା]

↑ "Patient information: Xiidra® (ZYE-druh) (lifitegrast ophthalmic solution) 5% for topical ophthalmic use" (PDF). Novartis. June 2020. Archived (PDF) from the original on 2021-02-13. Retrieved 2021-02-05.
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "Lifitegrast Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 5 March 2021. Retrieved 22 November 2021.
↑ ^୩.୦ ^୩.୧ ^୩.୨ "Lifitegrast". SPS - Specialist Pharmacy Service. 8 February 2016. Archived from the original on 11 December 2021. Retrieved 23 November 2021.
↑ ^୪.୦ ^୪.୧ "Xiidra: Withdrawal of the marketing authorisation application". Archived from the original on 14 November 2021. Retrieved 23 November 2021.
↑ "Lifitegrast ophthalmic (Xiidra) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 November 2020. Retrieved 23 November 2021.
↑ "Lifitegrast Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 28 October 2016. Retrieved 23 November 2021.

[1] "Patient information: Xiidra® (ZYE-druh) (lifitegrast ophthalmic solution) 5% for topical ophthalmic use" (PDF). Novartis. June 2020. Archived (PDF) from the original on 2021-02-13. Retrieved 2021-02-05.

[AHFS2021-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "Lifitegrast Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 5 March 2021. Retrieved 22 November 2021.

[SP2021-3] ୩.୦ ^୩.୧ ^୩.୨ "Lifitegrast". SPS - Specialist Pharmacy Service. 8 February 2016. Archived from the original on 11 December 2021. Retrieved 23 November 2021.

[EPAR2021-4] ୪.୦ ^୪.୧ "Xiidra: Withdrawal of the marketing authorisation application". Archived from the original on 14 November 2021. Retrieved 23 November 2021.

[5] "Lifitegrast ophthalmic (Xiidra) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 November 2020. Retrieved 23 November 2021.

[6] "Lifitegrast Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 28 October 2016. Retrieved 23 November 2021.

[୧]

[୨]

[୩]

[୪]

[୫]

[୬]