ବେଟାକ୍ସୋଲୋଲ

ବେଟାକ୍ସୋଲୋଲ
Clinical data
Pronunciation	be tax' oh lol
Trade names	Kerlone
AHFS/Drugs.com	Systemic: monograph; Eye: monograph
MedlinePlus	a609023
Pregnancy; category	AU: C ; ;
Routes of; administration	By mouth, eye drop
Legal status
Legal status	℞ (Prescription only);
Pharmacokinetic data
Bioavailability	89%
Metabolism	Liver
Elimination half-life	14–22 hours
Excretion	Kidney (20%)
Identifiers
	IUPAC name (RS)-1-{4-[2-(cyclopropylmethoxy)ethyl]-; phenoxy}-3-(isopropylamino)propan-2-ol;
ECHA InfoCard	100.113.058
Chemical and physical data
Formula	C18H29NO3
Molar mass	୩୦୭.୪୩ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O(CCc1ccc(OCC(O)CNC(C)C)cc1)CC2CC2;
	InChI InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3 ; Key:NWIUTZDMDHAVTP-UHFFFAOYSA-N ;
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ବେଟାକ୍ସୋଲୋଲ, ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ଏକ ବେପାର ନାମ କେର୍ଲୋନ, ହେଉଛି ଗ୍ଲୁକୋମା ଏବଂ ଉଚ୍ଚ ରକ୍ତଚାପର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ଏକ ଔଷଧ । ^[୨] ଏହା ଆଖିର ଚାପକୁ ପ୍ରାୟ ୩୦% ହ୍ରାସ କରିଥାଏ । ^[୩] ରକ୍ତଚାପ ପାଇଁ ଏହା ପ୍ରଥମ ଧାଡି ଚିକିତ୍ସା ନୁହେଁ | ^[୪] ଏହା ପାଟିରେ ଦିଆଯାଏ କିମ୍ବା ଆଖି ବୁନ୍ଦା ଭାବରେ ବ୍ୟବହୃତ ହୁଏ । ^[୧]

ପାଟିରେ ଦିଆଯଉଥିବା ଔଷଧର ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ସ୍ୱଳ୍ପ ହୃଦଗତି ହାର, ନିମ୍ନ ରକ୍ତଚାପ, ଥକାପଣ, ମୁଣ୍ଡ ବୁଲାଇବା, ଅବସାଦ, ଶୋଇବାରେ ଅସୁବିଧା, ସ୍ମୃତି ଶକ୍ତି ହ୍ରାସ ଏବଂ ଯୌନ କ୍ରିୟା ଅସୁବିଧା ହୋଇପାରେ । ^[୨] ଅଧିକ ମାତ୍ରାରେ ଏହା ବ୍ରୋଙ୍କୋସ୍ପାଜ୍ମ ସୃଷ୍ଟି କରିପାରେ । ^[୧] ଆଖି ବୁନ୍ଦାର ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆଖିର ଜ୍ୱାଳା ହୋଇପାରେ । ^[୫] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ | ^[୪] ଏହା ଏକ ସିଲେକ୍ଟିଭ୍ ବିଟା<sub id="mwJg">1</sub> ରିସେପ୍ଟର ବ୍ଲକର୍ ଔଷଧ ।^[୧] ଆଖିରେ ଆକ୍ୱିଅସ ହ୍ୟୁମର ଉତ୍ପାଦନ ହ୍ରାସ କରି ଏହା କାର୍ଯ୍ୟକ୍ଷମ ହୁଏ । ^[୩]

ବେଟାକ୍ସୋଲୋଲ ୧୯୭୫ରେ ପେଟେଣ୍ଟ କରାଯାଇଥିଲା ଏବଂ ୧୯୮୩ରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା । ^[୬] ଏହା ଏକ ସାଧାରଣ ଔଷଧ । ^[୨] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ୫ମିଲି ଆଖି ବୁନ୍ଦା ମୂଲ୍ୟ ୨ ପାଉଣ୍ଡ ଖର୍ଚ୍ଚ ହୋଇଥାଏ । ^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହାର ମୂଲ୍ୟ ୨୧ ଡଲାର । ^[୭]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ "Betaxolol". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 15 May 2021. Retrieved 10 January 2022.
↑ ^୨.୦ ^୨.୧ ^୨.୨ "Betaxolol". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 15 May 2021. Retrieved 10 January 2022.
↑ ^୩.୦ ^୩.୧ "Betaxolol (EENT) Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 24 January 2021. Retrieved 10 January 2022.
↑ ^୪.୦ ^୪.୧ "Betaxolol (Systemic) Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 6 August 2021. Retrieved 10 January 2022.
↑ ^୫.୦ ^୫.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1224. ISBN 978-0857114105.
↑ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 461. ISBN 9783527607495. Archived from the original on 2017-09-08. Retrieved 2021-03-21.
↑ "Betaxolol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 6 October 2016. Retrieved 10 January 2022.

[autogen1-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ "Betaxolol". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 15 May 2021. Retrieved 10 January 2022.

[Liv2022-2] ୨.୦ ^୨.୧ ^୨.୨ "Betaxolol". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 15 May 2021. Retrieved 10 January 2022.

[AHFS2022Eye-3] ୩.୦ ^୩.୧ "Betaxolol (EENT) Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 24 January 2021. Retrieved 10 January 2022.

[AHFS2022Oral-4] ୪.୦ ^୪.୧ "Betaxolol (Systemic) Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 6 August 2021. Retrieved 10 January 2022.

[BNF81-5] ୫.୦ ^୫.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1224. ISBN 978-0857114105.

[Fis2006-6] Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 461. ISBN 9783527607495. Archived from the original on 2017-09-08. Retrieved 2021-03-21.

[7] "Betaxolol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 6 October 2016. Retrieved 10 January 2022.

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