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ଫ୍ଲୁନିଟ୍ରାଜେପାମ

ଉଇକିପିଡ଼ିଆ‌ରୁ
ଫ୍ଲୁନିଟ୍ରାଜେପାମ
Clinical data
Pronunciation/ˌflnɪˈtræzɪpæm/
Trade namesRohypnol, others[୨]
SynonymsCircles, Forget Me Pill, La Rocha, Lunch Money Drug, Mexican Valium[୩]
Pregnancy
category
  • AU: C
Addiction
liability
High[୧]
Routes of
administration
By mouth
Legal status
Legal status
Pharmacokinetic data
Bioavailability64–77% (by mouth)
50% (suppository)
MetabolismLiver
Metabolites7-aminoflunitrazepam, desmethylflunitrazepam and 3-hydroxydesmethylflunitrazepam
Onset of actionRapid[୧]
Elimination half-life18–26 hours
ExcretionKidney
Identifiers
  • 5-(2-fluorophenyl)-1-methyl-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
ECHA InfoCard100.015.089 Edit this at Wikidata
Chemical and physical data
FormulaC16H12FN3O3
Molar mass୩୧୩.୨୯ g·mol−1
3D model (JSmol)
  • [O-][N+](C1=CC2=C(C=C1)N(C)C(CN=C2C3=CC=CC=C3F)=O)=O
  • InChI=1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3 checkY
  • Key:PPTYJKAXVCCBDU-UHFFFAOYSA-N checkY
  (verify)

ଫ୍ଲୁନିଟ୍ରାଜେପାମ, ଅନ୍ୟ ନାମମାନଙ୍କ ମଧ୍ୟରେ ରୋହିପ୍ନୋଲ୍ ଭାବରେ ମଧ୍ୟ ଜଣାଶୁଣା, ଏକ ବେଞ୍ଜୋଡାଏଜେପିନ ଯାହା ନିଦ୍ରାହୀନତା ଏବଂ ନିଶ୍ଚେତକ ଦେବାରେ ସାହାଯ୍ୟ କରିଥାଏ ।[୧] [୪] ଏହା ପ୍ରାରମ୍ଭିକ ସୁପାରିଶ କରାଯାଇଥିବା ଚିକିତ୍ସା ନୁହେଁ ଏବଂ କେବଳ ସ୍ୱଳ୍ପକାଳୀନ ବ୍ୟବହାର ପାଇଁ ସୁପାରିଶ କରାଯାଏ ।[୧] [୫]

ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଅପବ୍ୟବହାର ସଙ୍କଟ, ରାତି ସମୟ ଖାଇବା, ଦ୍ୱନ୍ଦ୍ୱ ଏବଂ ପ୍ରତ୍ୟାହାର ଲକ୍ଷଣ ଅନ୍ତର୍ଭୁକ୍ତ ଯଦି ଦୀର୍ଘକାଳୀନ ବ୍ୟବହାର ପରେ ହଠାତ୍ ବନ୍ଦ କରିଦିଆଯାଏ । [୧] [୬] [୭] ଅଧିକ ମାତ୍ରା ସେବନ କଲେ ଶ୍ୱାସ କ୍ରିୟା ହ୍ରାସ ହେବା ଏବଂ ମୃତ୍ୟୁ ହୋଇପାରେ ।[୭] ଦୀର୍ଘ ସମୟ ବ୍ୟବହାର କରିବା ପରେ ଧୀରେ ଧୀରେ ଔଷଧ କମେଇବା ପରେ ବନ୍ଦ କରାଯିବା ଆବଶ୍ୟକ। [୭]

ଫ୍ଲୁନିଟ୍ରାଜେପାମ ୧୯୬୨ ମସିହାରେ ପ୍ୟାଟେଣ୍ଟ ହୋଇଥିଲା ଏବଂ ୧୯୭୪ରେ ଚିକିତ୍ସା ବ୍ୟବହାରରେ ଆସିଥିଲା ।[୮] ଏହା ଯୁକ୍ତରାଷ୍ଟ୍ର, ଅଷ୍ଟ୍ରେଲିଆ ଏବଂ ନ୍ୟୁଜିଲ୍ୟାଣ୍ଡରେ ଆଇନଗତ ଭାବରେ ଉପଲବ୍ଧ ନୁହେଁ ଏବଂ ୟୁରୋପର କିଛି ଅଂଶରେ ଏହା ସୀମିତ ଅଟେ । [୬] ଏହାକୁ ଏକ ସମ୍ପର୍କ ବଳାତ୍କାର ଔଷଧ ବୋଲି କୁହାଯାଇଛି, [୯] [୧୦] ଯଦିଓ ଏଥିରେ ସମ୍ପୃକ୍ତ ବଳାତ୍କାର ମାମଲାର ରିପୋର୍ତ ବ‌ହୁତ କମ୍ । [୧୧]

ଆଧାର[ସମ୍ପାଦନା]

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