ନେଟୁପିଟାଣ୍ଟ/ପାଲୋନୋସେଟ୍ରନ

ନେଟୁପିଟାଣ୍ଟ/ପାଲୋନୋସେଟ୍ରନ
Combination of
Netupitant	NK1 receptor antagonist
Palonosetron	5-HT3 receptor antagonist
Clinical data
Trade names	Akynzeo
AHFS/Drugs.com	monograph
MedlinePlus	a614053
data	EU EMA: yes; US DailyMed: Akynzeo;
Pregnancy; category	AU: B3 ; US: N (Not classified yet) ; ;
Routes of; administration	By mouth, intravenous
Legal status
Legal status	AU: S4 (Prescription only) ; UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ; ℞ (Prescription only);

ଇଂରାଜୀ ଲିଙ୍କ

https://or.wikipedia.org/wiki/Netupitant/palonosetron

ନେଟୁପିଟାଣ୍ଟ/ପାଲୋନୋସେଟ୍ରନ (ଇଂରାଜୀ ଭାଷାରେ Netupitant/palonosetron), ଆକିନଜେଓ ଏହାରଏକ ବେପାର ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା ତୀବ୍ର ଏବଂ ବିଳମ୍ବିତ କେମୋଥେରାପି ଜନିତ ଅଇ ଏବଂ ବାନ୍ତି ରୋକିବା ପାଇଁ ବ୍ୟବ‌ହୃତ ହୁଏ ।^[୫] ଏହା ପାଟିରେ ଦିଆଯାଏ | ^[୫] ଏହା ଡେକ୍ସାମେଥାଜୋନ ସହିତ ବ୍ୟବହୃତ ହୁଏ ।^[୫]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମୁଣ୍ଡବିନ୍ଧା, କୋଷ୍ଠକାଠିନ୍ୟ ଏବଂ ଥକାପଣ ହୋଇପାରେ ।^[୩] ସାମାନ୍ୟରୁ ମଧ୍ୟମ ଯକୃତ କିମ୍ବା ବୃକ୍କ‌କ ଜନିତ ସମସ୍ୟା ଥିଲେ ଔଷଧ ମାତ୍ରା ସଜାଡିବା ଆବଶ୍ୟକ ନାହିଁ ।^[୫] ଗର୍ଭାବସ୍ଥାରେ ବ୍ୟବହାର ସୁପାରିଶ କରାଯାଏ ନାହିଁ ।^[୬] ନେଟୁପିଟାଣ୍ଟ ହେଉଛି ଏକ ଏନ‌କେ_୧ ଅଭିଗ୍ରାହକ ଅବରୋଧକ ଏବଂ ପାଲୋନୋସେଟ୍ରନ୍ ହେଉଛି ୫-ଏଚଟି_୩ ଅଭିଗ୍ରାହକ ଅବରୋଧକ | ^[୩]

ଏହି ମିଶ୍ରଣକୁ ୨୦୧୪ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ର ଏବଂ ୨୦୧୫ରେ ୟୁରୋପରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦନ କରାଯାଇଥିଲା ।^[୫] ^[୩] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ଏକ ମାତ୍ରାର ମୂଲ୍ୟ ପ୍ରାୟ ୭୦ ପାଉଣ୍ଡ ଅଟେ ।^[୬] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ରାଶିର ମୂଲ୍ୟ ପ୍ରାୟ ୬୮୦ ଡଲାର ଅଟେ ।| ^[୭]

ଆଧାର

↑ ^୧.୦ ^୧.୧ "Netupitant / palonosetron (Akynzeo) Use During Pregnancy". Drugs.com. 22 October 2018. Archived from the original on 19 December 2019. Retrieved 19 March 2020.
↑ "Fosnetupitant / palonosetron (Akynzeo for Injection) Use During Pregnancy". Drugs.com. 22 October 2018. Archived from the original on 19 March 2020. Retrieved 19 March 2020.
↑ ^୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ "Akynzeo EPAR". European Medicines Agency (EMA). 19 March 2020. Archived from the original on 19 March 2020. Retrieved 19 March 2020.
↑ "Akynzeo 300 mg/0.5 mg hard capsules - Summary of Product Characteristics (SmPC)". (emc). 11 February 2020. Archived from the original on 19 March 2020. Retrieved 19 March 2020.
↑ ^୫.୦ ^୫.୧ ^୫.୨ ^୫.୩ ^୫.୪ "Netupitant/Palonosetron Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 12 November 2021.
↑ ^୬.୦ ^୬.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 456. ISBN 978-0857114105.
↑ "Akynzeo Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 19 April 2021. Retrieved 12 November 2021.

[Drugs.com_pregnancy-1] ୧.୦ ^୧.୧ "Netupitant / palonosetron (Akynzeo) Use During Pregnancy". Drugs.com. 22 October 2018. Archived from the original on 19 December 2019. Retrieved 19 March 2020.

[Drugs.com_injection_pregnancy-2] "Fosnetupitant / palonosetron (Akynzeo for Injection) Use During Pregnancy". Drugs.com. 22 October 2018. Archived from the original on 19 March 2020. Retrieved 19 March 2020.

[EPAR2021-3] ୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ "Akynzeo EPAR". European Medicines Agency (EMA). 19 March 2020. Archived from the original on 19 March 2020. Retrieved 19 March 2020.

[4] "Akynzeo 300 mg/0.5 mg hard capsules - Summary of Product Characteristics (SmPC)". (emc). 11 February 2020. Archived from the original on 19 March 2020. Retrieved 19 March 2020.

[AHFS2021-5] ୫.୦ ^୫.୧ ^୫.୨ ^୫.୩ ^୫.୪ "Netupitant/Palonosetron Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 12 November 2021.

[BNF81-6] ୬.୦ ^୬.୧ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 456. ISBN 978-0857114105.

[7] "Akynzeo Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 19 April 2021. Retrieved 12 November 2021.

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