ଟ୍ରାଇହେପ୍ଟାନଏନ

ଟ୍ରାଇହେପ୍ଟାନଏନ
Clinical data
Trade names	Dojolvi
Synonyms	UX007
AHFS/Drugs.com
data	US DailyMed: Triheptanoin;
Routes of; administration	By mouth
Legal status
Legal status	CA: ℞-only ; US: ℞-only ;
Identifiers
	IUPAC name 2,3-di(heptanoyloxy)propyl heptanoate or glyceryl triheptanoate;
ECHA InfoCard	100.009.681
Chemical and physical data
Formula	C24H44O6
Molar mass	୪୨୮.୬୧ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCC(=O)OCC(COC(=O)CCCCCC)OC(=O)CCCCCC;
	InChI InChI=1S/C24H44O6/c1-4-7-10-13-16-22(25)28-19-21(30-24(27)18-15-12-9-6-3)20-29-23(26)17-14-11-8-5-2/h21H,4-20H2,1-3H3 ; Key:PJHKBYALYHRYSK-UHFFFAOYSA-N ;

ଇଂରାଜୀ ଲିଙ୍କ

https://or.wikipedia.org/wiki/Triheptanoin

ଟ୍ରାଇହେପ୍ଟାନଏନ (ଇଂରାଜୀ ଭାଷାରେ Triheptanoin), ଡୋଜୋଲଭି ଏକ ବେପାର ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା ଲମ୍ବା-ଚେନ୍ ଫ୍ୟାଟି ଏସିଡ୍ ଅକ୍ସିଡେସନ ରୋଗମାନଙ୍କର (LC-FAOD) ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୨] ଏଥିରେ ପାଇରୁଭେଟ କାର୍ବୋକ୍ସିଲେଜ ଅଭାବ ଏବଂ କାର୍ନିଟିନ୍ ପାମିଟଏଲଟ୍ରାନ୍ସଫ୍ରେଜ୍ II ଅଭାବ ହୋଇଥାଏ ।^[୩] ^[୪] ଏହା ପାଟିରେ ଦିଆଯାଏ।

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ପେଟ ଯନ୍ତ୍ରଣା, ତରଳ ଝାଡ଼ା, ବାନ୍ତି ଏବଂ ଅଇ ଲାଗେ ।^[୨] ଅଗ୍ନାଶୟ ଅଭାବ ଥିବା ଅନ୍ତନଳୀରେ ମାଲଆବସର୍ପସନ ହୋଇପାରେ । ଏହା ଏକ ଉତ୍ପାଦିତ ମଧ୍ୟମ-ଚେନ୍ ଟ୍ରାଇଗ୍ଲିସେରାଇଡ୍ ଏବଂ କ୍ୟାଲୋରୀ ଏବଂ ଫ୍ୟାଟି ଏସିଡର ଉତ୍ସ ଅଟେ । ^[୫]

୨୦୨୦ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ପାଇଁ ଟ୍ରାଇହେପ୍ଟାନଏନ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୨] ୨୦୨୨ ସୁଦ୍ଧା ଏହା ୟୁରୋପ କିମ୍ବା ବ୍ରିଟେନରେ ଅନୁମୋଦିତ ନୁହେଁ ।^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୨୦୨୨ ସୁଦ୍ଧା ୫୦୦ ମିଲି ପାଇଁ ଏହାର ମୂଲ୍ୟ ୫୬୦୦ ଡଲାର ଅଟେ ।^[୬]

ଆଧାର

↑ "Summary Basis of Decision (SBD) for Dojolvi". Health Canada. Archived from the original on 30 May 2022. Retrieved 29 May 2022.
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "Dojolvi- triheptanoin liquid". DailyMed. 30 June 2020. Archived from the original on 2 August 2021. Retrieved 24 September 2020.
↑ "Pyruvate Carboxylase Deficiency". NORD (National Organization for Rare Disorders). Archived from the original on 23 October 2022. Retrieved 4 November 2022.
↑ RESERVED, INSERM. "Orphanet: Carnitine palmitoyl transferase II deficiency, myopathic form". www.orpha.net (in ଇଂରାଜୀ). Archived from the original on 27 November 2021. Retrieved 4 November 2022.
↑ ^୫.୦ ^୫.୧ "Triheptanoin". SPS - Specialist Pharmacy Service. 2 February 2018. Archived from the original on 31 January 2022. Retrieved 4 November 2022.
↑ "Dojolvi Prices, Coupons, Copay & Patient Assistance". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 16 September 2021. Retrieved 4 November 2022.

[1] "Summary Basis of Decision (SBD) for Dojolvi". Health Canada. Archived from the original on 30 May 2022. Retrieved 29 May 2022.

[PI2022-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ "Dojolvi- triheptanoin liquid". DailyMed. 30 June 2020. Archived from the original on 2 August 2021. Retrieved 24 September 2020.

[3] "Pyruvate Carboxylase Deficiency". NORD (National Organization for Rare Disorders). Archived from the original on 23 October 2022. Retrieved 4 November 2022.

[4] RESERVED, INSERM. "Orphanet: Carnitine palmitoyl transferase II deficiency, myopathic form". www.orpha.net (in ଇଂରାଜୀ). Archived from the original on 27 November 2021. Retrieved 4 November 2022.

[SPS2022-5] ୫.୦ ^୫.୧ "Triheptanoin". SPS - Specialist Pharmacy Service. 2 February 2018. Archived from the original on 31 January 2022. Retrieved 4 November 2022.

[6] "Dojolvi Prices, Coupons, Copay & Patient Assistance". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 16 September 2021. Retrieved 4 November 2022.

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