ଆବସିକ୍ସିମାବ

ଆବସିକ୍ସିମାବ
Monoclonal antibody
Type	Fab fragment
Source	Chimeric (mouse/human)
Target	CD41 7E3
Clinical data
Trade names	Reopro
Synonyms	Abcixifiban, c7E3 Fab
AHFS/Drugs.com	monograph
data	US DailyMed: Abciximab;
Pregnancy; category	US: C (Risk not ruled out) ; ;
Routes of; administration	Intravenous (IV)
ATC code	B01AC13 (WHO) ;
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ;
Identifiers
CAS Number	143653-53-6 ;
DrugBank	DB00054 ;
ChemSpider	none;
UNII	X85G7936GV;
KEGG	D02778 ;
ChEMBL	CHEMBL1201584 ;
Chemical and physical data
Formula	C2101H3229N551O673S15
Molar mass	୪୭,୪୫୬.୦୩ g·mol−1
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ଆବସିକ୍ସିମାବ, ଏକ ବେପାର ନାମ ରିଓପ୍ରୋ, ଏକ ଔଷଧ ଯାହା ପରକ୍ୟୁଟାନିଅସ କରୋନାରୀ ଆଞ୍ଜିଓପ୍ଲାଷ୍ଟି ( PCI) କରାଯାଉଥିବା ସମୟରେ ପ୍ଲାଟେଲେଟ ଏକତ୍ରିକରଣକୁ ବାଧା ଦେବାକୁ ବ୍ୟବହୃତ ହୁଏ । ^[୩] ଏହା ଏକ ଶିରାରେ ଇଞ୍ଜେକ୍ସନ ଆକାରରେ ଦିଆଯାଏ । ^[୪] ପୂର୍ଣ୍ଣ ପ୍ରଭାବ ୧୦ ମିନିଟ୍ ମଧ୍ୟରେ ଆରମ୍ଭ ହୋଇ ୪୮ ଘଣ୍ଟା ପର୍ଯ୍ୟନ୍ତ ରହିଥାଏ । ^[୪]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ରକ୍ତସ୍ରାବ, ନିମ୍ନ ରକ୍ତଚାପ, ବାନ୍ତି, ମୁଣ୍ଡବିନ୍ଧା ଏବଂ ପ୍ରାନ୍ତୀୟ ଫୁଲା ହୋଇପାରେ । ଅ^[୩] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆନାଫାଇଲାକ୍ସିସ୍ ଏବଂ କମ୍ ପ୍ଲାଲେଟ୍ ରହିପାରେ । ^[୪] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ | ^[୪] ଏହା ଏକ ଗ୍ଲାଇକୋପ୍ରୋଟିନ୍_ IIb / IIIa ଇନହିବିଟର ଯାହା ପ୍ଲାଟେଲେଟମାନଙ୍କୁ ଏକତ୍ର ହେବାକୁ ବାଧା ଦେଇଥାଏ । ^[୪]

୧୯୮୪ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ Abciximabକୁ ଅନୁମୋଦନ କରାଯାଇଥିଲା ।^[୩] ସେଠାରେ ଏହାର ୧୦ ମିଗ୍ରାର ମୂଲ୍ୟ ୨୦୨୨ ମସିହାରେ ୧୩୦୦ ଡଲାର ଥିଲା । ^[୫]

ଆଧାର

↑ Toronto Notes: Comprehensive medical reference and review for the Medical Council of Canada Qualifying Exam Part I and the United States Medical Licensing Exam Step 2 (32nd ed.). Toronto, Ontario, Canada.: Toronto Notes for Medical Students, Inc. ISBN 978-1-927363-26-3.
↑ "ReoPro Abciximab" (PDF). Janssen Pharmaceutical Companies. U.S. Food and Drug Administration. August 2019.
↑ ^୩.୦ ^୩.୧ ^୩.୨ "Abciximab Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 4 January 2021. Retrieved 13 January 2022.
↑ ^୪.୦ ^୪.୧ ^୪.୨ ^୪.୩ ^୪.୪ "Abciximab Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 4 January 2021. Retrieved 13 January 2022.
↑ "ReoPro Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 10 February 2018. Retrieved 13 January 2022.

[1] Toronto Notes: Comprehensive medical reference and review for the Medical Council of Canada Qualifying Exam Part I and the United States Medical Licensing Exam Step 2 (32nd ed.). Toronto, Ontario, Canada.: Toronto Notes for Medical Students, Inc. ISBN 978-1-927363-26-3.

[2] "ReoPro Abciximab" (PDF). Janssen Pharmaceutical Companies. U.S. Food and Drug Administration. August 2019.

[AHFS2022-3] ୩.୦ ^୩.୧ ^୩.୨ "Abciximab Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 4 January 2021. Retrieved 13 January 2022.

[autogen1-4] ୪.୦ ^୪.୧ ^୪.୨ ^୪.୩ ^୪.୪ "Abciximab Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 4 January 2021. Retrieved 13 January 2022.

[5] "ReoPro Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 10 February 2018. Retrieved 13 January 2022.

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