ଆଇସୋପ୍ରେନାଲିନ

ଆଇସୋପ୍ରେନାଲିନ
Clinical data
Trade names	Isoprenaline Macure, others
AHFS/Drugs.com	monograph
MedlinePlus	a601236
Pregnancy; category	AU: A ; US: C (Risk not ruled out) ; ;
Routes of; administration	Inhalation (80–120 μg), intravenous injection (IV)
Legal status
Legal status	AU: S4 (Prescription only) ; ℞ (Prescription only);
Pharmacokinetic data
Elimination half-life	~2 minutes
Identifiers
	IUPAC name (RS)-4-[1-hydroxy-2-(isopropylamino)ethyl]benzene-1,2-diol;
ECHA InfoCard	100.028.807
Chemical and physical data
Formula	C11H17NO3
Molar mass	୨୧୧.୨୬ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)NCC(O)c1cc(O)c(O)cc1;
	InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3 ; Key:JWZZKOKVBUJMES-UHFFFAOYSA-N ;
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ଆଇସୋପ୍ରେନାଲିନ, ଯାହାକୁ ଆଇସୋପ୍ରୋଟେରେନୋଲ ମଧ୍ୟ କୁହାଯାଏ, ଏକ ଔଷଧ ଯାହା ସ୍ୱଳ୍ପ ହୃଦ୍‌ଗତି ହାର, ହୃତ୍‌ପିଣ୍ଡ ଅବରୋଧ, ଶକ୍ ଏବଂ ବ୍ରୋଙ୍କୋସ୍ପାଜ୍ମ ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୨] ଶକ୍ ନିମନ୍ତେ ସାଧାରଣତଃ ନର୍ ଏପିନେଫ୍ରିନ ପସନ୍ଦ କରାଯାଏ ।^[୨] ଏହା ସାଧାରଣତ ଇଞ୍ଜେକ୍ସନ୍ ସାହାଯ୍ୟରେ ଦିଆଯାଏ ।^[୨]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମୁଣ୍ଡବିନ୍ଧା, ଉଦ୍‌ବେଗ, ଅସ୍ପଷ୍ଟ ଦୃଷ୍ଟି, ଦୃତ ହୃତ୍ ସ୍ପନ୍ଦନ, ଛାତି ଯନ୍ତ୍ରଣା, ଅଧିକ ଝାଳ ଏବଂ କମ୍ପନ ହୋଇପାରେ ।^[୨] କାର୍ଡିଆକ୍ ଗ୍ଲାଇକୋସାଇଡ୍ ବିଷାକ୍ତ ବ୍ୟକ୍ତିଙ୍କଠାରେ ଏହା ବ୍ୟବହାର କରାଯିବା ଉଚିତ୍ ନୁହେଁ ।^[୨] ଗର୍ଭାବସ୍ଥାରେ ବ୍ୟବହାର ନିରାପଦ ଦେଖାଯାଏ ।^[୩] ଏହା ଏକ ଅଣ-ଚୟନକାରୀ β ଆଡ୍ରେନୋସେପ୍ଟର ଆଗୋନିଷ୍ଟ ।^[୪]

୧୯୪୭ ମସିହାରେ ଆମେରିକାରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଆଇସୋପ୍ରେନାଲିନ୍ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୦.୨ ମିଗ୍ରା ଇଞ୍ଜେକ୍ସନ ପାଇଁ ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ ୧୯୦ ଡଲାର ଖର୍ଚ୍ଚ ହେଉଥିଲା ।^[୬] ପାଟିରେ ଏବଂ ନିଶ୍ୱାସପ୍ରାପ୍ତ ଫର୍ମଗୁଡ଼ିକ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ବ୍ୟବସାୟିକ ଭିତ୍ତିରେ ଏହି ଔଷଧ ଆଉ ଉପଲବ୍ଧ ହେଉନାହିଁ ।^[୨] ଏହା ବିଭିନ୍ନ ବେପାର ନାମରେ ଉପଲବ୍ଧ ।^[୧]

ଆଧାର

↑ ^୧.୦ ^୧.୧ "Isoprenaline international brands". Drugs.com. Archived from the original on 26 June 2019. Retrieved 21 June 2017.
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ ^୨.୫ "Isoproterenol Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 28 November 2021.
↑ "Isoproterenol Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 November 2020. Retrieved 28 November 2021.
↑ "Label: Isoproterenol hydrochloride injection, solution". NIH DailyMed. September 10, 2013. Archived from the original on 11 January 2017. Retrieved 21 June 2017.
↑ Mozayani, Ashraf; Raymon, Lionel (2003). Handbook of Drug Interactions: A Clinical and Forensic Guide (in ଇଂରାଜୀ). Springer Science & Business Media. pp. 541–542. ISBN 9781592596546. Archived from the original on 2019-12-15. Retrieved 2021-10-18.
↑ "Isoproterenol Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 27 January 2021. Retrieved 28 November 2021.

[brands-1] ୧.୦ ^୧.୧ "Isoprenaline international brands". Drugs.com. Archived from the original on 26 June 2019. Retrieved 21 June 2017.

[AHFS2021-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ ^୨.୫ "Isoproterenol Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 28 November 2021.

[3] "Isoproterenol Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 November 2020. Retrieved 28 November 2021.

[PI2021-4] "Label: Isoproterenol hydrochloride injection, solution". NIH DailyMed. September 10, 2013. Archived from the original on 11 January 2017. Retrieved 21 June 2017.

[Mozayan2003book-5] Mozayani, Ashraf; Raymon, Lionel (2003). Handbook of Drug Interactions: A Clinical and Forensic Guide (in ଇଂରାଜୀ). Springer Science & Business Media. pp. 541–542. ISBN 9781592596546. Archived from the original on 2019-12-15. Retrieved 2021-10-18.

[6] "Isoproterenol Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 27 January 2021. Retrieved 28 November 2021.

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