ପିରୋକ୍ସିକାମ

ପିରୋକ୍ସିକାମ
Clinical data
Pronunciation	/paɪˈrɒksɪˌkæm/
Trade names	Feldene, others
Synonyms	Piroksikam, piroxikam
AHFS/Drugs.com	monograph
MedlinePlus	a684045
Pregnancy; category	AU: C ;
Routes of; administration	By mouth
Legal status
Legal status	AU: S4 (Prescription only) ; CA: ℞-only ; UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ;
Pharmacokinetic data
Protein binding	99%
Metabolism	Liver-mediated hydroxylation and glucuronidation
Elimination half-life	50 hours
Excretion	Urine, faeces
Identifiers
	IUPAC name 4-Hydroxy-2-methyl-N-(2-pyridinyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;
ECHA InfoCard	100.048.144
Chemical and physical data
Formula	C15H13N3O4S
Molar mass	୩୩୧.୩୫ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES OC=2c1ccccc1S(=O)(=O)N(C)C=2C(=O)Nc3ccccn3;
	InChI InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20) ; Key:QYSPLQLAKJAUJT-UHFFFAOYSA-N ;
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ପିରୋକ୍ସିକାମ ହେଉଛି ଏକ ନନଷ୍ଟେରଏଡାଲ୍ ଆଣ୍ଟି-ଇନ୍‌ଫ୍ଲାମେଟୋରୀ ଔଷଧ (NSAID) ଯାହା ଯନ୍ତ୍ରଣା ଏବଂ ପ୍ରଦାହର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୪] ଆର୍ଥ୍ରାଇଟିସ୍ ଏବଂ ଋତୁଶୂଳ ପରି ଅବସ୍ଥାରେ ଏହା ଦିଆଯାଇପାରେ ।^[୪] ଏହା ପାଟିରେ ଦିଆଯାଏ କିମ୍ବା ଚର୍ମରେ ପ୍ରୟୋଗ କରାଯାଏ ।^[୪]^[୫]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ବୁକୁଜ୍ୱାଳା, ଅଇ, ତରଳ ଝାଡ଼ା, ଲାଲ ଦାଗ, ମୁଣ୍ଡବିନ୍ଧା, ଫୁଲା ଏବଂ କାନନାଦ ହୋଇପାରେ ।^[୪] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆନାଫାଇଲକ୍‌ସିସ, ବୃକ୍‌କ ସମସ୍ୟା, ଖାଦ୍ୟନଳୀ ରକ୍ତସ୍ରାବ, ହୃଦ ରୋଗ, ହୃଦ୍‌ପାତ ଏବଂ ଉଚ୍ଚ ରକ୍ତଚାପ ହୋଇପାରେ ।^[୪] ଗର୍ଭାବସ୍ଥାର ଉତ୍ତର ଭାଗରେ ଔଷଧ ବ୍ୟବହାର କଲେ ଶିଶୁର କ୍ଷତି ହୋଇପାରେ ।^[୪] ଏହାର ନାମ ଅକ୍ସିକାମ ଔଷଧ ପରିବାରରେ ଅଛି ଏବଂ କ‌କ୍ସ-୧ ଓ କ‌କ୍ସ-୨କୁ ଅବରୋଧ କରି କାର୍ଯ୍ୟକ୍ଷମ ହୁଏ ।^[୪]

ପିରୋକ୍ସିକାମ ୧୯୬୮ ମସିହାରେ ପେଟେଣ୍ଟ ହୋଇଥିଲା ଏବଂ ୧୯୭୯ରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୬] ଏହା ଏକ ସାଧାରଣ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ ।^[୫] ଯୁକ୍ତରାଜ୍ୟରେ ଏକ ମାସର ଔଷଧ ବାବଦ ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ £୫ ଖର୍ଚ୍ଚ ହୋଇଥାଏ ।^[୫] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ଔଷଧ ଖର୍ଚ୍ଚ ପ୍ରାୟ ୩୦ ଡଲାର ଅଟେ ।^[୭] ଏହାକୁ ଅନେକ ବେପାର ନାମରେ ବିକ୍ରି କରାଯାଏ ।^[୧]

ଆଧାର

1 2 "Piroxicam Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 August 2021. Retrieved 28 October 2021.
↑ "Archive copy" (PDF). Archived (PDF) from the original on 2021-08-28. Retrieved 2021-01-28.{{cite web}}: CS1 maint: archived copy as title (link)
1 2 3 Brayfield, A, ed. (14 January 2014). "Piroxicam". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Archived from the original on 28 August 2021. Retrieved 24 June 2014.
1 2 3 4 5 6 7 "Piroxicam Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 October 2021. Retrieved 28 October 2021.
1 2 3 BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1196. ISBN 978-0857114105.
↑ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 519. ISBN 9783527607495. Archived from the original on 2020-07-10. Retrieved 2020-09-06.
↑ "Piroxicam Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 24 January 2021. Retrieved 28 October 2021.

[drugsInternat-1] 1 2 "Piroxicam Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 August 2021. Retrieved 28 October 2021.

[2] "Archive copy" (PDF). Archived (PDF) from the original on 2021-08-28. Retrieved 2021-01-28.{{cite web}}: CS1 maint: archived copy as title (link)

[MD-3] 1 2 3 Brayfield, A, ed. (14 January 2014). "Piroxicam". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Archived from the original on 28 August 2021. Retrieved 24 June 2014.

[AHFS2021-4] 1 2 3 4 5 6 7 "Piroxicam Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 October 2021. Retrieved 28 October 2021.

[BNF81-5] 1 2 3 BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1196. ISBN 978-0857114105.

[Fis2006-6] Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 519. ISBN 9783527607495. Archived from the original on 2020-07-10. Retrieved 2020-09-06.

[7] "Piroxicam Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 24 January 2021. Retrieved 28 October 2021.

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