ମାଭାକାମଟେନ

ମାଭାକାମଟେନ
Clinical data
Trade names	Camzyos
Synonyms	MYK-461
AHFS/Drugs.com	monograph
data	US DailyMed: Mavacamten;
Routes of; administration	By mouth
Legal status
Legal status	AU: S4 (Prescription only) ; US: ℞-only ;
Identifiers
	IUPAC name 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione;
ECHA InfoCard	100.269.298
Chemical and physical data
Formula	C15H19N3O2
Molar mass	୨୭୩.୩୪ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N1C(=O)NC(N[C@@H](C)C2=CC=CC=C2)=CC1=O;
	InChI InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1; Key:RLCLASQCAPXVLM-NSHDSACASA-N;

ମାଭାକାମଟେନ, ଇଂରାଜୀ ଭାଷାରେ Mavacamten, ହେଉଛି ଏକ ଔଷଧ ଯାହା ହାଇପରଟ୍ରଫିକ ଅବଷ୍ଟ୍ରକ୍ଟିଭ୍ କାର୍ଡିଓମାଇଓପାଥି (HCOM) ରୋଗର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୨] ଏହା ପାଟିରେ ଦିଆଯାଏ ।^[୨]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମୁଣ୍ଡ ବୁଲାଏ ଏବଂ ବେହୋସ ହୋଇଯାଏ ।^[୨] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ହୃଦ୍‌ପାତ ହୋଇପାରେ ।^[୨] ଗର୍ଭାବସ୍ଥାରେ ବ୍ୟବହାର କଲେ ଶିଶୁର କ୍ଷତି ହୋଇପାରେ ।^[୨] ଏହା ଏକ ହୃତ୍‌ପିଣ୍ଡ ମାୟୋସିନ୍ ଇନହିବିଟର ।^[୨]

୨୦୨୨ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଡାକ୍ତରୀ ବ୍ୟବହାର ପାଇଁ ମାଭାକାମଟେନ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୨] ୨୦୨୨ ସୁଦ୍ଧା ଏହା ୟୁରୋପ କିମ୍ବା ଯୁକ୍ତରାଜ୍ୟରେ ଉପଲବ୍ଧ ନୁହେଁ ।^[୩] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏକ ମାସର ଔଷଧର ଖର୍ଚ୍ଚ ମୂଲ୍ୟ ପ୍ରାୟ ୭,୮୦୦ ଡଲାର ।^[୪]

ଆଧାର

↑ "Archive copy". Archived from the original on 2022-11-13. Retrieved 2022-11-29.{{cite web}}: CS1 maint: archived copy as title (link)
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ ^୨.୫ ^୨.୬ ^୨.୭ "Camzyos- mavacamten capsule, gelatin coated". DailyMed. 28 April 2022. Archived from the original on 3 July 2022. Retrieved 15 May 2022."Camzyos- mavacamten capsule, gelatin coated". DailyMed. 28 April 2022. Archived from the original on 3 July 2022. Retrieved 15 May 2022.
↑ "Mavacamten". SPS - Specialist Pharmacy Service. 19 October 2018. Archived from the original on 24 June 2022. Retrieved 12 December 2022.
↑ "Camzyos Prices, Coupons, Copay & Patient Assistance". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 22 May 2023. Retrieved 12 December 2022.

[1] "Archive copy". Archived from the original on 2022-11-13. Retrieved 2022-11-29.{{cite web}}: CS1 maint: archived copy as title (link)

[PI2022-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ ^୨.୫ ^୨.୬ ^୨.୭ "Camzyos- mavacamten capsule, gelatin coated". DailyMed. 28 April 2022. Archived from the original on 3 July 2022. Retrieved 15 May 2022."Camzyos- mavacamten capsule, gelatin coated". DailyMed. 28 April 2022. Archived from the original on 3 July 2022. Retrieved 15 May 2022.

[SPS022-3] "Mavacamten". SPS - Specialist Pharmacy Service. 19 October 2018. Archived from the original on 24 June 2022. Retrieved 12 December 2022.

[4] "Camzyos Prices, Coupons, Copay & Patient Assistance". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 22 May 2023. Retrieved 12 December 2022.

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