"ସାଲାଇନ (ଔଷଧ)" ପୃଷ୍ଠାର ସଂସ୍କରଣଗୁଡ଼ିକ ମଧ୍ୟରେ ତଫାତ
ଅଧିକ ତଥ୍ୟ ଦିଆଗଲା |
ଅଧିକ ତଥ୍ୟ ଦିଆଗଲା |
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୧୦୦ କ ଧାଡ଼ି: | ୧୦୦ କ ଧାଡ଼ି: | ||
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ଅତ୍ୟଧିକ ସାଲାଇନ ଦେଲେ [[ତରଳ ପଦାର୍ଥ ଓଭରଲୋଡ]] ([[:en:fluid overload|fluid overload]]), [[ଇଡିମା]] ([[:en:edema|swelling]]), [[ହାଇପରକ୍ଲୋରେମିକ ଏସିଡୋସିସ]] ([[:en:hyperchloremic acidosis|acidosis]]) ଓ [[ଅଧିକ ରକ୍ତ ସୋଡ଼ିଅମ]] ([[:en:high blood sodium|high blood sodium]]) ହୋଇପାରେ । <ref name=BNF69>{{cite book|title=British national formulary : BNF 69|date=2015|publisher=British Medical Association|isbn=9780857111562|page=683, 770|edition=69}}</ref><ref name=Pro2017/> ଦୀର୍ଘକାଳୀନ [[ଅଳ୍ପ ରକ୍ତ ସୋଡ଼ିଅମ]] ([[:en:low blood sodium|low blood sodium]]) ଥିବା ରୋଗୀଙ୍କୁ ଅଧିକ ସାଲାଇନ ଦେଲେ [[ଅସମୋଟିକ ଡିମାୟେଲିନେସନ ସିଣ୍ଡ୍ରୋମ]] ([[:en:osmotic demyelination syndrome|osmotic demyelination syndrome]]) ହୋଇପାରେ ।<ref name=BNF69/> ଏହା [[ଭଲ୍ୟୁମ ଏକ୍ସପାଣ୍ଡର]] ([[:en:Volume_expander#Crystalloids|crystalloid]]) ଶ୍ରେଣୀର ଏକ ଔଷଧ ।<ref>{{cite book|last1=Marini|first1=John J.|last2=Wheeler|first2=Arthur P.|title=Critical Care Medicine: The Essentials|date=2010|publisher=Lippincott Williams & Wilkins|isbn=9780781798396|page=54|url=https://books.google.ca/books?id=jmxl0ERFvYgC&pg=PA54|language=en}}</ref> |
ଅତ୍ୟଧିକ ସାଲାଇନ ଦେଲେ [[ତରଳ ପଦାର୍ଥ ଓଭରଲୋଡ]] ([[:en:fluid overload|fluid overload]]), [[ଇଡିମା]] ([[:en:edema|swelling]]), [[ହାଇପରକ୍ଲୋରେମିକ ଏସିଡୋସିସ]] ([[:en:hyperchloremic acidosis|acidosis]]) ଓ [[ଅଧିକ ରକ୍ତ ସୋଡ଼ିଅମ]] ([[:en:high blood sodium|high blood sodium]]) ହୋଇପାରେ । <ref name=BNF69>{{cite book|title=British national formulary : BNF 69|date=2015|publisher=British Medical Association|isbn=9780857111562|page=683, 770|edition=69}}</ref><ref name=Pro2017/> ଦୀର୍ଘକାଳୀନ [[ଅଳ୍ପ ରକ୍ତ ସୋଡ଼ିଅମ]] ([[:en:low blood sodium|low blood sodium]]) ଥିବା ରୋଗୀଙ୍କୁ ଅଧିକ ସାଲାଇନ ଦେଲେ [[ଅସମୋଟିକ ଡିମାୟେଲିନେସନ ସିଣ୍ଡ୍ରୋମ]] ([[:en:osmotic demyelination syndrome|osmotic demyelination syndrome]]) ହୋଇପାରେ ।<ref name=BNF69/> ଏହା [[ଭଲ୍ୟୁମ ଏକ୍ସପାଣ୍ଡର]] ([[:en:Volume_expander#Crystalloids|crystalloid]]) ଶ୍ରେଣୀର ଏକ ଔଷଧ ।<ref>{{cite book|last1=Marini|first1=John J.|last2=Wheeler|first2=Arthur P.|title=Critical Care Medicine: The Essentials|date=2010|publisher=Lippincott Williams & Wilkins|isbn=9780781798396|page=54|url=https://books.google.ca/books?id=jmxl0ERFvYgC&pg=PA54|language=en}}</ref> ସାଧାରଣତଃ ଏହା ୯ଗ୍ରା:/ଲିଟରର (୦.୯%) ଏକ [[ସ୍ଟେରାଇଲ ଦ୍ରବଣ]] ([[:en:Sterilization (microbiology)|sterile]]) ଯାହାକୁ [[ନର୍ମାଲ ସାଲାଇନ]] ([[:en:normal saline|normal saline]]) କୁହାଯାଏ ।<ref name=Pro2017/> ଏହାଠାରୁ ଅଧିକ ଗାଢ଼ ବା କମ ଗାଢ଼ ସାଲାଇନ ମଧ୍ୟ ବ୍ୟବହାର କରାଯାଏ ।<ref>{{cite web|title=Hypertonic Saline - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/hypertonic-saline.html|website=www.drugs.com|accessdate=14 January 2017}}</ref><ref>{{cite book|last1=Pestana|first1=Carlos|title=Fluids and Electrolytes in the Surgical Patient|date=2000|publisher=Lippincott Williams & Wilkins|isbn=9780781724258|page=11|url=https://books.google.ca/books?id=CfCuIUwv3pEC&pg=PA11|language=en}}</ref> |
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The medical use of saline began around 1831.<ref>{{cite book|last1=Bozzetti|first1=Federico|last2=Staun|first2=Michael|last3=Gossum|first3=Andre van|title=Home Parenteral Nutrition, 2nd Edition|date=2014|publisher=CABI|isbn=9781780643113|page=4|url=https://books.google.ca/books?id=fnYXBgAAQBAJ&pg=PA4|language=en}}</ref> It is on the [[World Health Organization's List of Essential Medicines]], the most effective and safe medicines needed in a [[health system]].<ref name=WHO19th>{{cite web|title=WHO Model List of Essential Medicines (19th List)|url=http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|work=World Health Organization|accessdate=8 December 2016|date=April 2015}}</ref> The wholesale cost in the [[developing world]] is about 0.60 to 4.20 USD per liter of normal saline.<ref name=ERC2014>{{cite web|title=Sodium Chloride in Water|url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=SC09A&s_year=2014&year=2014&str=0%2E9%25&desc=Sodium%20Chloride%20In%20Water&pack=new&frm=SOLUTION&rte=IV&class_code2=26.2.&supplement=&class_name=Parenteral%20solutions%20correcting%20water%2C%20electrolyte%2C%20%26%20acid-base%20disturbances|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}</ref> |
The medical use of saline began around 1831.<ref>{{cite book|last1=Bozzetti|first1=Federico|last2=Staun|first2=Michael|last3=Gossum|first3=Andre van|title=Home Parenteral Nutrition, 2nd Edition|date=2014|publisher=CABI|isbn=9781780643113|page=4|url=https://books.google.ca/books?id=fnYXBgAAQBAJ&pg=PA4|language=en}}</ref> It is on the [[World Health Organization's List of Essential Medicines]], the most effective and safe medicines needed in a [[health system]].<ref name=WHO19th>{{cite web|title=WHO Model List of Essential Medicines (19th List)|url=http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|work=World Health Organization|accessdate=8 December 2016|date=April 2015}}</ref> The wholesale cost in the [[developing world]] is about 0.60 to 4.20 USD per liter of normal saline.<ref name=ERC2014>{{cite web|title=Sodium Chloride in Water|url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=SC09A&s_year=2014&year=2014&str=0%2E9%25&desc=Sodium%20Chloride%20In%20Water&pack=new&frm=SOLUTION&rte=IV&class_code2=26.2.&supplement=&class_name=Parenteral%20solutions%20correcting%20water%2C%20electrolyte%2C%20%26%20acid-base%20disturbances|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}</ref> |
୦୯:୦୮, ୧୮ ଅଗଷ୍ଟ ୨୦୧୭ ଅନୁସାରେ କରାଯାଇଥିବା ବଦଳ
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AHFS/Drugs.com | FDA Professional Drug Information |
Routes of administration | intravenous, topical, subcutaneous |
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ସାଲାଇନ (ଇଂରାଜୀ ଭାଷାରେ Saline, ଅନ୍ୟ ନାମ ସାଲାଇନ ସଲ୍ୟୁସନ/saline solution) ଏକ ଦ୍ରବଣ ଯେଉଁଥିରେ ସୋଡ଼ିଅମ କ୍ଲୋରାଇଡ (sodium chloride) ଓ ପାଣି ମିଶିଥାଏ; ଏହା ଅନେକ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ହୁଏ ।[୧] ଏହା କ୍ଷତ ସଫା କରିବାରେ ସାହାଯ୍ୟ କରେ, କଣ୍ଟାକ୍ଟ ଲେନ୍ସ (contact lens) ବାହାର କରିବାରେ ସାହାଯ୍ୟ କରେ ଓ ଶୁଷ୍କ ଆଖିରେ (dry eyes) ପକାଯାଏ । ନିର୍ଜଳନ (dehydration) ଥିଲେ ବିଶେଷତଃ ପାକଅନ୍ତନଳୀ ପ୍ରଦାହ (gastroenteritis) ଓ ଡାଏବେଟିକ କିଟୋଏସିଡୋସିସ (diabetic ketoacidosis) ନିର୍ଜଳନରେ ଏହା ଶିରାଭ୍ୟନ୍ତର ଇନଫ୍ୟୁଜନ (injection into a vein) ଆକାରରେ ଦିଆଯାଏ । [୨] ଇଞ୍ଜେକସନ ଆକାରରେ ଦିଆଯାଉଥିବା ଅନ୍ୟ ଔଷଧମାନଙ୍କୁ ପତଳା କରିବାକୁ ଏହା ମିଶାଯାଏ । [୧]
ଅତ୍ୟଧିକ ସାଲାଇନ ଦେଲେ ତରଳ ପଦାର୍ଥ ଓଭରଲୋଡ (fluid overload), ଇଡିମା (swelling), ହାଇପରକ୍ଲୋରେମିକ ଏସିଡୋସିସ (acidosis) ଓ ଅଧିକ ରକ୍ତ ସୋଡ଼ିଅମ (high blood sodium) ହୋଇପାରେ । [୨][୧] ଦୀର୍ଘକାଳୀନ ଅଳ୍ପ ରକ୍ତ ସୋଡ଼ିଅମ (low blood sodium) ଥିବା ରୋଗୀଙ୍କୁ ଅଧିକ ସାଲାଇନ ଦେଲେ ଅସମୋଟିକ ଡିମାୟେଲିନେସନ ସିଣ୍ଡ୍ରୋମ (osmotic demyelination syndrome) ହୋଇପାରେ ।[୨] ଏହା ଭଲ୍ୟୁମ ଏକ୍ସପାଣ୍ଡର (crystalloid) ଶ୍ରେଣୀର ଏକ ଔଷଧ ।[୩] ସାଧାରଣତଃ ଏହା ୯ଗ୍ରା:/ଲିଟରର (୦.୯%) ଏକ ସ୍ଟେରାଇଲ ଦ୍ରବଣ (sterile) ଯାହାକୁ ନର୍ମାଲ ସାଲାଇନ (normal saline) କୁହାଯାଏ ।[୧] ଏହାଠାରୁ ଅଧିକ ଗାଢ଼ ବା କମ ଗାଢ଼ ସାଲାଇନ ମଧ୍ୟ ବ୍ୟବହାର କରାଯାଏ ।[୪][୫]
ଆଧାର
- ↑ ୧.୦ ୧.୧ ୧.୨ ୧.୩ "Sodium Chloride Injection - FDA prescribing information, side effects and uses". www.drugs.com. Retrieved 14 January 2017.
- ↑ ୨.୦ ୨.୧ ୨.୨ British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 683, 770. ISBN 9780857111562.
- ↑ Marini, John J.; Wheeler, Arthur P. (2010). Critical Care Medicine: The Essentials (in ଇଂରାଜୀ). Lippincott Williams & Wilkins. p. 54. ISBN 9780781798396.
- ↑ "Hypertonic Saline - FDA prescribing information, side effects and uses". www.drugs.com. Retrieved 14 January 2017.
- ↑ Pestana, Carlos (2000). Fluids and Electrolytes in the Surgical Patient (in ଇଂରାଜୀ). Lippincott Williams & Wilkins. p. 11. ISBN 9780781724258.